Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
The effect of ventilation rate on outcome in adults receiving cardiopulmonary resuscitation
Abstract: Aim:To investigate whether a ventilation rate <= 10 breaths min(-1) in adult cardiac arrest patients treated with tracheal intubation and chest compressions in a prehospital setting is associated with improved Return of Spontaneous Circulation (ROSC), survival to hospital discharge and one-year survival with favourable neurological outcome, compared to a ventilation rate >10 breaths min(-1). Methods: In this retrospective study, prospectively acquired data were analysed. Ventilation rates were measured with end-tidal CO, and ventilation pressures. Analyses were corrected for age, sex, compression rate, compression depth, initial heart rhythm and cause of cardiac arrest. Results: 337 of 652 patients met the inclusion criteria. Hyperventilation was common, with 85% of the patients ventilated >10 breaths min(-1). The mean ventilation rate was 15.3 breaths min(-1). The corrected odds ratio (OR) of ventilating >10 breaths min(-1) for achieving ROSC was 0.91 (95% CI: 0.49-1.71, p = 0.78), the uncorrected OR of ventilating >10 breaths min(-1) for survival to hospital discharge was 0.91 (95% CI: 0.30-2.77, p = 0.78), and the uncorrected OR of ventilating >10 breaths min(1) for one-year survival with a favourable neurological outcome was 0.59 (95% CI: 0.19-1.87, p = 0.32). A logistic regression with continuous ventilation rate showed no significant relation with ROSC, and a ROC curve for ROSC showed a poor predictive performance (AUC: 0.52, 95% CI: 0.46-0.58), suggesting no other adequate cut-off value for ventilation rate. Conclusion: A ventilation rate <= 10 breaths min(-1) was not associated with significantly improved outcomes compared to a ventilation rate >10 breaths min(-1). No other adequate cut-off value could be proposed.
The effect of ventilation rate on outcome in adults receiving cardiopulmonary resuscitation
Abstract: Aim:To investigate whether a ventilation rate <= 10 breaths min(-1) in adult cardiac arrest patients treated with tracheal intubation and chest compressions in a prehospital setting is associated with improved Return of Spontaneous Circulation (ROSC), survival to hospital discharge and one-year survival with favourable neurological outcome, compared to a ventilation rate >10 breaths min(-1). Methods: In this retrospective study, prospectively acquired data were analysed. Ventilation rates were measured with end-tidal CO, and ventilation pressures. Analyses were corrected for age, sex, compression rate, compression depth, initial heart rhythm and cause of cardiac arrest. Results: 337 of 652 patients met the inclusion criteria. Hyperventilation was common, with 85% of the patients ventilated >10 breaths min(-1). The mean ventilation rate was 15.3 breaths min(-1). The corrected odds ratio (OR) of ventilating >10 breaths min(-1) for achieving ROSC was 0.91 (95% CI: 0.49-1.71, p = 0.78), the uncorrected OR of ventilating >10 breaths min(-1) for survival to hospital discharge was 0.91 (95% CI: 0.30-2.77, p = 0.78), and the uncorrected OR of ventilating >10 breaths min(1) for one-year survival with a favourable neurological outcome was 0.59 (95% CI: 0.19-1.87, p = 0.32). A logistic regression with continuous ventilation rate showed no significant relation with ROSC, and a ROC curve for ROSC showed a poor predictive performance (AUC: 0.52, 95% CI: 0.46-0.58), suggesting no other adequate cut-off value for ventilation rate. Conclusion: A ventilation rate <= 10 breaths min(-1) was not associated with significantly improved outcomes compared to a ventilation rate >10 breaths min(-1). No other adequate cut-off value could be proposed.
The effect of ventilation rate on outcome in adults receiving cardiopulmonary resuscitation
Vissers, G. (Autor:in) / Duchatelet, C. (Autor:in) / Huybrechts, S. A. (Autor:in) / Wouters, Kristien (Autor:in) / Hachimi-Idrissi, S. (Autor:in) / Monsieurs, Koen (Autor:in)
01.01.2019
0300-9572 ; Resuscitation
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
DDC:
690
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