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Validation of virtual water phantom software for pre-treatment verification of single-isocenter multiple-target stereotactic radiosurgery
Objectiu múltiple; SRS; Fantasma virtual ; Objetivo múltiple; SRS; Fantasma virtual ; Multiple‐target; SRS; Virtual phantom ; The aim of this study was to benchmark the accuracy of the VIrtual Phantom Epid dose Reconstruction (VIPER) software for pre-treatment dosimetric verification of multiple-target stereotactic radiosurgery (SRS). VIPER is an EPID-based method to reconstruct a 3D dose distribution in a virtual phantom from in-air portal images. Validation of the VIPER dose calculation was assessed using several MLC-defined fields for a 6 MV photon beam. Central axis percent depth doses (PDDs) and output factors were measured with an ionization chamber in a water tank, while dose planes at a depth of 10 cm in a solid flat phantom were acquired with radiochromic films. The accuracy of VIPER for multiple-target SRS plan verification was benchmarked against Monte Carlo simulations. Eighteen multiple-target SRS plans designed with the Eclipse treatment planning system were mapped to a cylindrical water phantom. For each plan, the 3D dose distribution reconstructed by VIPER within the phantom was compared with the Monte Carlo simulation, using a 3D gamma analysis. Dose differences (VIPER vs. measurements) generally within 2% were found for the MLC-defined fields, while film dosimetry revealed gamma passing rates (GPRs) ≥95% for a 3%/1 mm criteria. For the 18 multiple-target SRS plans, average 3D GPRs greater than 93% and 98% for the 3%/2 mm and 5%/2 mm criteria, respectively. Our results validate the use of VIPER as a dosimetric verification tool for pre-treatment QA of single-isocenter multiple-target SRS plans. The method requires no setup time on the linac and results in an accurate 3D characterization of the delivered dose.
Validation of virtual water phantom software for pre-treatment verification of single-isocenter multiple-target stereotactic radiosurgery
Objectiu múltiple; SRS; Fantasma virtual ; Objetivo múltiple; SRS; Fantasma virtual ; Multiple‐target; SRS; Virtual phantom ; The aim of this study was to benchmark the accuracy of the VIrtual Phantom Epid dose Reconstruction (VIPER) software for pre-treatment dosimetric verification of multiple-target stereotactic radiosurgery (SRS). VIPER is an EPID-based method to reconstruct a 3D dose distribution in a virtual phantom from in-air portal images. Validation of the VIPER dose calculation was assessed using several MLC-defined fields for a 6 MV photon beam. Central axis percent depth doses (PDDs) and output factors were measured with an ionization chamber in a water tank, while dose planes at a depth of 10 cm in a solid flat phantom were acquired with radiochromic films. The accuracy of VIPER for multiple-target SRS plan verification was benchmarked against Monte Carlo simulations. Eighteen multiple-target SRS plans designed with the Eclipse treatment planning system were mapped to a cylindrical water phantom. For each plan, the 3D dose distribution reconstructed by VIPER within the phantom was compared with the Monte Carlo simulation, using a 3D gamma analysis. Dose differences (VIPER vs. measurements) generally within 2% were found for the MLC-defined fields, while film dosimetry revealed gamma passing rates (GPRs) ≥95% for a 3%/1 mm criteria. For the 18 multiple-target SRS plans, average 3D GPRs greater than 93% and 98% for the 3%/2 mm and 5%/2 mm criteria, respectively. Our results validate the use of VIPER as a dosimetric verification tool for pre-treatment QA of single-isocenter multiple-target SRS plans. The method requires no setup time on the linac and results in an accurate 3D characterization of the delivered dose.
Validation of virtual water phantom software for pre-treatment verification of single-isocenter multiple-target stereotactic radiosurgery
Calvo‐Ortega, Juan‐Francisco (Autor:in) / Greer, Peter B. (Autor:in) / Moragues‐Femenía, Sandra (Autor:in) / Laosa‐Bello, Coral (Autor:in) / Casals‐Farran, Joan (Autor:in) / Hermida López, Marcelino (Autor:in) / Institut Català de la Salut / Calvo-Ortega JF, Moragues-Femenía S, Laosa-Bello C, Casals-Farran J Servicio de Oncología Radioterápica, Hospital Quirónsalud, Barcelona, Spain. Servicio de Oncología Radioterápica, Hospital Universitari Dexeus, Barcelona, Spain. Greer PB Department of Radiation Oncology, Calvary Mater Newcastle Hospital, Newcastle, NSW, 2298, Australia. School of Mathematical and Physical Sciences, University of Newcastle, Newcastle, NSW, 2300, Australia. Hermida-López M Servei de Física i Protecció Radiològica, Vall d'Hebron Hospital Universitari, Barcelona, Spain / Vall d'Hebron Barcelona Hospital Campus
01.06.2021
000653274900001
Scientia
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Imaging , AND EQUIPMENT::Equipment and Supplies::Phantoms , DIAGNÓSTICOS Y TERAPÉUTICOS::equipos y suministros::modelos en imaginología , AND EQUIPMENT::Therapeutics::Radiotherapy::Radiosurgery , CIENCIA DE LA INFORMACIÓN::Ciencias de la información::metodologías computacionales::soporte lógico (informática) , Medicina - Informàtica , Radiocirurgia , TÉCNICAS Y EQUIPOS ANALÍTICOS , ANALYTICAL , INFORMATION SCIENCE::Information Science::Computing Methodologies::Software , DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::radioterapia::radiocirugía , DIAGNOSTIC AND THERAPEUTIC TECHNIQUES
DDC:
690
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