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Candidate Gene Mapping Identifies Genomic Variations in the Fire Blight Susceptibility genes HIPM and DIPM across the Malus Germplasm
Development of apple (Malus domestica) cultivars resistant to fire blight, a devastating bacterial disease caused by Erwinia amylovora, is a priority for apple breeding programs. Towards this goal, the inactivation of members of the HIPM and DIPM gene families with a role in fire blight susceptibility (S genes) can help achieve sustainable tolerance. We have investigated the genomic diversity of HIPM and DIPM genes in Malus germplasm collections and used a candidate gene-based association mapping approach to identify SNPs (single nucleotide polymorphisms) with significant associations to fire blight susceptibility. A total of 87 unique SNP variants were identified in HIPM and DIPM genes across 93 Malus accessions. Thirty SNPs showed significant associations (p < 0.05) with fire blight susceptibility traits, while two of these SNPs showed highly significant (p < 0.001) associations across two different years. This research has provided knowledge about genetic diversity in fire blight S genes in diverse apple accessions and identified candidate HIPM and DIPM alleles that could be used to develop apple cultivars with decreased fire blight susceptibility via marker-assisted breeding or biotechnological approaches
Candidate Gene Mapping Identifies Genomic Variations in the Fire Blight Susceptibility genes HIPM and DIPM across the Malus Germplasm
Development of apple (Malus domestica) cultivars resistant to fire blight, a devastating bacterial disease caused by Erwinia amylovora, is a priority for apple breeding programs. Towards this goal, the inactivation of members of the HIPM and DIPM gene families with a role in fire blight susceptibility (S genes) can help achieve sustainable tolerance. We have investigated the genomic diversity of HIPM and DIPM genes in Malus germplasm collections and used a candidate gene-based association mapping approach to identify SNPs (single nucleotide polymorphisms) with significant associations to fire blight susceptibility. A total of 87 unique SNP variants were identified in HIPM and DIPM genes across 93 Malus accessions. Thirty SNPs showed significant associations (p < 0.05) with fire blight susceptibility traits, while two of these SNPs showed highly significant (p < 0.001) associations across two different years. This research has provided knowledge about genetic diversity in fire blight S genes in diverse apple accessions and identified candidate HIPM and DIPM alleles that could be used to develop apple cultivars with decreased fire blight susceptibility via marker-assisted breeding or biotechnological approaches
Candidate Gene Mapping Identifies Genomic Variations in the Fire Blight Susceptibility genes HIPM and DIPM across the Malus Germplasm
Tegtmeier, R. (Autor:in) / Pompili, V. (Autor:in) / Singh, J. (Autor:in) / Micheletti, D. (Autor:in) / Silva, K. (Autor:in) / Malnoy, M. (Autor:in) / Khan, A. (Autor:in) / Tegtmeier, R. / Pompili, V. / Singh, J.
01.01.2020
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
DDC:
690
British Library Online Contents | 2012
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