Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Short-term exposure to fine particulate matter and pneumonia-related hospitalizations: a systematic review and meta-analysis
Previous epidemiological reports have emphasized the impact of ambient particulate matter (PM) on pneumonia-related hospitalizations. However, these reports vary across different study populations. We aimed to evaluate the impact of short-term exposure to PM on hospital admissions due to pneumonia. A systematic literature review was performed to identify studies quantifying the impact of PM ≤2.5 μ g m ^−3 (PM _2.5 ) and PM ≤10 μ g m ^−3 (PM _10 ) on pneumonia-related hospitalizations. A meta-analysis was performed by using pooled analyses of each pollutant with a random effects model. Subgroup analyses were performed according to various lag times and age groups, along with meta-regression analyses. A total of ten studies were eligible for analysis. In the overall population, a 10 μ g m ^−3 increase in the daily PM _2.5 was associated with an increased risk ratio (RR) of hospitalization for pneumonia (pooled RR 1.007, 95% confidence interval [CI]: 1.000–1.014 per 10 μ g m ^−3 increase), but the PM _10 was not (pooled RR 1.008, 95% CI: 0.998–1.018 per 10 μ g m ^−3 increase). A lag effect was not observed in the subgroup analysis of different lag times. In the subgroup analysis of elderly individuals (≥65 years), both the PM _2.5 and PM _10 resulted in increased RRs for pneumonia-related hospitalizations, with pooled RRs of 1.026 (95% CI: 1.006–1.047 per 10 μ g m ^−3 increase) and 1.016 (95% CI: 1.013–1.019 per 10 μ g m ^−3 increase), respectively. By contrast, studies that included young patients revealed a nonsignificant relationship between exposure to high levels of PM _2.5 and pneumonia-related hospitalizations (RR 1.003, 95% CI: 0.999–1.008 per 10 μ g m ^−3 increase). In the meta-regression analysis, results from recent study periods indicated that the effect of PM _2.5 on pneumonia-related hospitalizations was less than that of earlier studies ( P = 0.009). Our results suggest that PM _2.5 and PM _10 may affect elderly individuals in terms of pneumonia-related hospitalizations, which may vary over time.
Short-term exposure to fine particulate matter and pneumonia-related hospitalizations: a systematic review and meta-analysis
Previous epidemiological reports have emphasized the impact of ambient particulate matter (PM) on pneumonia-related hospitalizations. However, these reports vary across different study populations. We aimed to evaluate the impact of short-term exposure to PM on hospital admissions due to pneumonia. A systematic literature review was performed to identify studies quantifying the impact of PM ≤2.5 μ g m ^−3 (PM _2.5 ) and PM ≤10 μ g m ^−3 (PM _10 ) on pneumonia-related hospitalizations. A meta-analysis was performed by using pooled analyses of each pollutant with a random effects model. Subgroup analyses were performed according to various lag times and age groups, along with meta-regression analyses. A total of ten studies were eligible for analysis. In the overall population, a 10 μ g m ^−3 increase in the daily PM _2.5 was associated with an increased risk ratio (RR) of hospitalization for pneumonia (pooled RR 1.007, 95% confidence interval [CI]: 1.000–1.014 per 10 μ g m ^−3 increase), but the PM _10 was not (pooled RR 1.008, 95% CI: 0.998–1.018 per 10 μ g m ^−3 increase). A lag effect was not observed in the subgroup analysis of different lag times. In the subgroup analysis of elderly individuals (≥65 years), both the PM _2.5 and PM _10 resulted in increased RRs for pneumonia-related hospitalizations, with pooled RRs of 1.026 (95% CI: 1.006–1.047 per 10 μ g m ^−3 increase) and 1.016 (95% CI: 1.013–1.019 per 10 μ g m ^−3 increase), respectively. By contrast, studies that included young patients revealed a nonsignificant relationship between exposure to high levels of PM _2.5 and pneumonia-related hospitalizations (RR 1.003, 95% CI: 0.999–1.008 per 10 μ g m ^−3 increase). In the meta-regression analysis, results from recent study periods indicated that the effect of PM _2.5 on pneumonia-related hospitalizations was less than that of earlier studies ( P = 0.009). Our results suggest that PM _2.5 and PM _10 may affect elderly individuals in terms of pneumonia-related hospitalizations, which may vary over time.
Short-term exposure to fine particulate matter and pneumonia-related hospitalizations: a systematic review and meta-analysis
Hyung-Jun Kim (Autor:in) / Hyun Woo Lee (Autor:in) / Jimyung Park (Autor:in) / Chang Hyun Lee (Autor:in) / Chang-Hoon Lee (Autor:in)
2020
Aufsatz (Zeitschrift)
Elektronische Ressource
Unbekannt
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