Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Occupational exposure to traditional and emerging organophosphate esters: A comparison of levels across different sources and blood distribution
Currently, there is limited knowledge regarding occupational exposure of traditional and emerging organophosphate esters (OPEs) from e-waste and automobile dismantling activities, and their distribution within the human blood. In the present study, we collected dust and urine samples from e-waste (ED) (n = 91 and 130, respectively) and automobile dismantling (AD) plants (n = 93 and 94, respectively), as well as serum-plasma-whole blood samples (sets from 128 participants) within ED areas for analyzing traditional and emerging organophosphate tri-esters (tri-OPEs) and organophosphate di-esters (di-OPEs). Median concentration of ∑tri-OPEs and ∑di-OPEs in dust (37,400 and 9,000 ng/g in ED, and 27,000 and 14,700 ng/g in AD areas, respectively) and urine samples (11.8 and 21.9 ng/mL in ED areas, and 17.2 and 15.0 ng/mL in AD areas, respectively) indicated that both e-waste and automobile dismantling activities served as important pollution source for OPEs. Dust ingestion has been evidenced to be the main exposure pathway compared to dermal absorption and inhalation. The median concentration (ng/mL) of OPEs in blood matrices descended order as follow: whole blood (13.1) > serum (11.6) > plasma (10.4) for ∑tri-OPEs, and plasma (3.51) > serum (0.36) > whole blood (0.23) for ∑di-OPEs. Concentration ratios of OPEs varied across blood matrices, depending on the compounds, suggesting that the essentiality of appropriate biomonitoring matrix for conducting comprehensive exposure assessments.
Occupational exposure to traditional and emerging organophosphate esters: A comparison of levels across different sources and blood distribution
Currently, there is limited knowledge regarding occupational exposure of traditional and emerging organophosphate esters (OPEs) from e-waste and automobile dismantling activities, and their distribution within the human blood. In the present study, we collected dust and urine samples from e-waste (ED) (n = 91 and 130, respectively) and automobile dismantling (AD) plants (n = 93 and 94, respectively), as well as serum-plasma-whole blood samples (sets from 128 participants) within ED areas for analyzing traditional and emerging organophosphate tri-esters (tri-OPEs) and organophosphate di-esters (di-OPEs). Median concentration of ∑tri-OPEs and ∑di-OPEs in dust (37,400 and 9,000 ng/g in ED, and 27,000 and 14,700 ng/g in AD areas, respectively) and urine samples (11.8 and 21.9 ng/mL in ED areas, and 17.2 and 15.0 ng/mL in AD areas, respectively) indicated that both e-waste and automobile dismantling activities served as important pollution source for OPEs. Dust ingestion has been evidenced to be the main exposure pathway compared to dermal absorption and inhalation. The median concentration (ng/mL) of OPEs in blood matrices descended order as follow: whole blood (13.1) > serum (11.6) > plasma (10.4) for ∑tri-OPEs, and plasma (3.51) > serum (0.36) > whole blood (0.23) for ∑di-OPEs. Concentration ratios of OPEs varied across blood matrices, depending on the compounds, suggesting that the essentiality of appropriate biomonitoring matrix for conducting comprehensive exposure assessments.
Occupational exposure to traditional and emerging organophosphate esters: A comparison of levels across different sources and blood distribution
Jingren Cui (Autor:in) / Yanhui Ge (Autor:in) / Meiqi Guo (Autor:in) / Lianying Zhang (Autor:in) / Shaohan Zhang (Autor:in) / Leicheng Zhao (Autor:in) / Yumeng Shi (Autor:in) / Mujtaba Baqar (Autor:in) / Yiming Yao (Autor:in) / Hongkai Zhu (Autor:in)
2024
Aufsatz (Zeitschrift)
Elektronische Ressource
Unbekannt
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