Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Development of ZnO/Ag nanoparticles supported polydopamine-modified montmorillonite nanocomposites with synergistic antibacterial performance
Abstract Nanocomposites are effective methods for the treatment of microbial infections. In this work, zinc oxide nanoparticles and silver nanoparticles were synthesized by a simple and mild method, and successfully loaded on polydopamine-modified montmorillonite (PDAMt) to prepare nanocomposites (ZnO/Ag/PDA-Mt) with potent antibacterial ability. The transmission electron microscope (TEM) showed that the nanoparticles in ZnO/Ag/PDA-Mt were quasi-spherical, and the particle size ranged from 5 nm to 45 nm. The energy dispersive spectroscopy (EDS)-mapping verified the presence of Zn, Ag, O, Al, Si and C elements in the synthesized ZnO/Ag/PDA-Mt. In addition, the antimicrobial activity of ZnO/Ag/PDA-Mt was also tested against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Due to the synergistic antibacterial effect between zinc oxide nanoparticles and silver nanoparticles, ZnO/Ag/PDA-Mt exhibited higher antiseptic activity than silver nanoparticles supported polydopamine-modified montmorillonite (Ag/PDA-Mt) and zinc oxide nanoparticles supported polydopamine-modified montmorillonite (ZnO/PDA-Mt). The biocompatibility of ZnO/Ag/PDA-Mt was evaluated by cytotoxicity assay. The results demonstrated that the ZnO/Ag/PDA-Mt nanocomposites have potential for antibacterial applications.
Graphical abstract Display Omitted
Highlights Zinc oxide nanoparticles and silver nanoparticles were successfully loaded on polydopamine-modified montmorillonite . Nanoparticles in ZnO/Ag/PDA-Mt were uniformly distributed on the nanosheet of PDA-Mt in spherical form. The ZnO/Ag/PDA-Mt can significantly enhance the antibacterial effect compared to Ag/PDA-Mt and ZnO/PDA-Mt. The ZnO/Ag/PDA-Mt showed high cytocompatibility in L929 fibroblasts.
Development of ZnO/Ag nanoparticles supported polydopamine-modified montmorillonite nanocomposites with synergistic antibacterial performance
Abstract Nanocomposites are effective methods for the treatment of microbial infections. In this work, zinc oxide nanoparticles and silver nanoparticles were synthesized by a simple and mild method, and successfully loaded on polydopamine-modified montmorillonite (PDAMt) to prepare nanocomposites (ZnO/Ag/PDA-Mt) with potent antibacterial ability. The transmission electron microscope (TEM) showed that the nanoparticles in ZnO/Ag/PDA-Mt were quasi-spherical, and the particle size ranged from 5 nm to 45 nm. The energy dispersive spectroscopy (EDS)-mapping verified the presence of Zn, Ag, O, Al, Si and C elements in the synthesized ZnO/Ag/PDA-Mt. In addition, the antimicrobial activity of ZnO/Ag/PDA-Mt was also tested against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Due to the synergistic antibacterial effect between zinc oxide nanoparticles and silver nanoparticles, ZnO/Ag/PDA-Mt exhibited higher antiseptic activity than silver nanoparticles supported polydopamine-modified montmorillonite (Ag/PDA-Mt) and zinc oxide nanoparticles supported polydopamine-modified montmorillonite (ZnO/PDA-Mt). The biocompatibility of ZnO/Ag/PDA-Mt was evaluated by cytotoxicity assay. The results demonstrated that the ZnO/Ag/PDA-Mt nanocomposites have potential for antibacterial applications.
Graphical abstract Display Omitted
Highlights Zinc oxide nanoparticles and silver nanoparticles were successfully loaded on polydopamine-modified montmorillonite . Nanoparticles in ZnO/Ag/PDA-Mt were uniformly distributed on the nanosheet of PDA-Mt in spherical form. The ZnO/Ag/PDA-Mt can significantly enhance the antibacterial effect compared to Ag/PDA-Mt and ZnO/PDA-Mt. The ZnO/Ag/PDA-Mt showed high cytocompatibility in L929 fibroblasts.
Development of ZnO/Ag nanoparticles supported polydopamine-modified montmorillonite nanocomposites with synergistic antibacterial performance
Liang, Han (Autor:in) / Wang, Huiyan (Autor:in) / Sun, Xuemei (Autor:in) / Xu, Wang (Autor:in) / Meng, Na (Autor:in) / Zhou, Ninglin (Autor:in)
Applied Clay Science ; 244
19.08.2023
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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