Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Risk of heatstroke in healthy elderly during heatwaves: A thermoregulatory modeling study
https://orcid.org/0000-0002-2945-4685
https://orcid.org/0000-0002-1840-050X
https://orcid.org/0000-0001-9824-3534
Abstract Background The frequency of temperature extremes is rising due to global warming. During heatwaves, the older adults are more likely to experience heat-related illnesses due to impaired sweating and cardiovascular functions. Few existing studies have systematically examined the healthy elderly's survival time and heatstroke/hyperthermia prevention measures during prolonged heatwaves. Objectives We aimed to systematically examine the core temperature responses of elderly during prolonged heatwaves and to predict survival time for the elderly using the modified Stolwijk thermoregulatory model. Methods The Stolwijk thermoregulatory model was modified to account for sweating and vasodilation alterations in the elderly during exposure to high temperatures. The model was then used to study the influence of environmental conditions on core temperature responses during the onset of classic heatstroke (Tcore = 40.5–40.6 °C) and to estimate survival time. Results Core temperature increases in three distinct stages under intense heat stress: an initial stage for thermoregulatory equilibrium alignment, a thermoregulatory steady-state, and a last rapid progression due to uncompensable heat stress resulting from dehydration. At the third stage, dehydration led to a fatal classic heatstroke. The increased air temperature and relative humidity shortened the survival duration. Conclusions The extended thermoregulation model was able to predict the core temperature responses of healthy elderly individuals exposed to extreme heat with reasonable accuracy (±0.3 °C). Furthermore, the model can be used to predict survival time and aid in the selection of efficient heatstroke prevention measures suited to the elderly.
Graphical abstract Display Omitted
Highlights An extended 6-segment Stolwijk model for the elderly was developed. Survival time was predicted by the extend elderly model. Core temperature increases in three stages under intense heat stress. Extended model could be used to provide preventive measures tailored to the elderly.
Risk of heatstroke in healthy elderly during heatwaves: A thermoregulatory modeling study
https://orcid.org/0000-0002-2945-4685
https://orcid.org/0000-0002-1840-050X
https://orcid.org/0000-0001-9824-3534
Abstract Background The frequency of temperature extremes is rising due to global warming. During heatwaves, the older adults are more likely to experience heat-related illnesses due to impaired sweating and cardiovascular functions. Few existing studies have systematically examined the healthy elderly's survival time and heatstroke/hyperthermia prevention measures during prolonged heatwaves. Objectives We aimed to systematically examine the core temperature responses of elderly during prolonged heatwaves and to predict survival time for the elderly using the modified Stolwijk thermoregulatory model. Methods The Stolwijk thermoregulatory model was modified to account for sweating and vasodilation alterations in the elderly during exposure to high temperatures. The model was then used to study the influence of environmental conditions on core temperature responses during the onset of classic heatstroke (Tcore = 40.5–40.6 °C) and to estimate survival time. Results Core temperature increases in three distinct stages under intense heat stress: an initial stage for thermoregulatory equilibrium alignment, a thermoregulatory steady-state, and a last rapid progression due to uncompensable heat stress resulting from dehydration. At the third stage, dehydration led to a fatal classic heatstroke. The increased air temperature and relative humidity shortened the survival duration. Conclusions The extended thermoregulation model was able to predict the core temperature responses of healthy elderly individuals exposed to extreme heat with reasonable accuracy (±0.3 °C). Furthermore, the model can be used to predict survival time and aid in the selection of efficient heatstroke prevention measures suited to the elderly.
Graphical abstract Display Omitted
Highlights An extended 6-segment Stolwijk model for the elderly was developed. Survival time was predicted by the extend elderly model. Core temperature increases in three stages under intense heat stress. Extended model could be used to provide preventive measures tailored to the elderly.
Risk of heatstroke in healthy elderly during heatwaves: A thermoregulatory modeling study
https://orcid.org/0000-0002-2945-4685
https://orcid.org/0000-0002-1840-050X
https://orcid.org/0000-0001-9824-3534
Abstract Background The frequency of temperature extremes is rising due to global warming. During heatwaves, the older adults are more likely to experience heat-related illnesses due to impaired sweating and cardiovascular functions. Few existing studies have systematically examined the healthy elderly's survival time and heatstroke/hyperthermia prevention measures during prolonged heatwaves. Objectives We aimed to systematically examine the core temperature responses of elderly during prolonged heatwaves and to predict survival time for the elderly using the modified Stolwijk thermoregulatory model. Methods The Stolwijk thermoregulatory model was modified to account for sweating and vasodilation alterations in the elderly during exposure to high temperatures. The model was then used to study the influence of environmental conditions on core temperature responses during the onset of classic heatstroke (Tcore = 40.5–40.6 °C) and to estimate survival time. Results Core temperature increases in three distinct stages under intense heat stress: an initial stage for thermoregulatory equilibrium alignment, a thermoregulatory steady-state, and a last rapid progression due to uncompensable heat stress resulting from dehydration. At the third stage, dehydration led to a fatal classic heatstroke. The increased air temperature and relative humidity shortened the survival duration. Conclusions The extended thermoregulation model was able to predict the core temperature responses of healthy elderly individuals exposed to extreme heat with reasonable accuracy (±0.3 °C). Furthermore, the model can be used to predict survival time and aid in the selection of efficient heatstroke prevention measures suited to the elderly.
Graphical abstract Display Omitted
Highlights An extended 6-segment Stolwijk model for the elderly was developed. Survival time was predicted by the extend elderly model. Core temperature increases in three stages under intense heat stress. Extended model could be used to provide preventive measures tailored to the elderly.
Risk of heatstroke in healthy elderly during heatwaves: A thermoregulatory modeling study
Ou, Yinping (Autor:in) / Wang, Faming (Autor:in) / Zhao, Jinping (Autor:in) / Deng, Qihong (Autor:in)
Building and Environment ; 237
16.04.2023
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Heatstroke at home: Prediction by thermoregulation modeling
| British Library Online Contents | 2018
Heatstroke at home: Prediction by thermoregulation modeling
| British Library Online Contents | 2018