Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts
https://orcid.org/0000-0003-4908-9715
https://orcid.org/0000-0002-3334-9458
https://orcid.org/0000-0002-7580-9547
https://orcid.org/0000-0002-6827-6084
https://orcid.org/0000-0002-9066-8893
https://orcid.org/0000-0001-9519-1935
https://orcid.org/0000-0002-3380-9717
https://orcid.org/0000-0002-1404-9222
https://orcid.org/0000-0002-7815-2632
https://orcid.org/0000-0002-1223-0909
https://orcid.org/0000-0002-9701-1130
https://orcid.org/0000-0003-2354-4652
https://orcid.org/0000-0002-6050-9904
https://orcid.org/0000-0003-4385-2097
https://orcid.org/0000-0001-9332-2241
https://orcid.org/0000-0001-8604-0190
https://orcid.org/0000-0002-4559-4127
https://orcid.org/0000-0001-9594-4140
https://orcid.org/0000-0002-7302-4789
Graphical abstract Display Omitted
Highlights The link between traffic noise and breast cancer was investigated pooling 8 cohorts. This large pooled multi-cohort study included 93,859 women. We found weak associations between road and railway noise and breast cancer risk. The association did not vary by estrogen receptor status. Aircraft noise was not associated with breast cancer incidence.
Abstract Background Environmental noise is an important environmental exposure that can affect health. An association between transportation noise and breast cancer incidence has been suggested, although current evidence is limited. We investigated the pooled association between long-term exposure to transportation noise and breast cancer incidence. Methods Pooled data from eight Nordic cohorts provided a study population of 111,492 women. Road, railway, and aircraft noise were modelled at residential addresses. Breast cancer incidence (all, estrogen receptor (ER) positive, and ER negative) was derived from cancer registries. Hazard ratios (HR) were estimated using Cox Proportional Hazards Models, adjusting main models for sociodemographic and lifestyle variables together with long-term exposure to air pollution. Results A total of 93,859 women were included in the analyses, of whom 5,875 developed breast cancer. The median (5th–95th percentile) 5-year residential road traffic noise was 54.8 (40.0–67.8) dB Lden, and among those exposed, the median railway noise was 51.0 (41.2–65.8) dB Lden. We observed a pooled HR for breast cancer (95 % confidence interval (CI)) of 1.03 (0.99–1.06) per 10 dB increase in 5-year mean exposure to road traffic noise, and 1.03 (95 % CI: 0.96–1.11) for railway noise, after adjustment for lifestyle and sociodemographic covariates. HRs remained unchanged in analyses with further adjustment for PM2.5 and attenuated when adjusted for NO2 (HRs from 1.02 to 1.01), in analyses using the same sample. For aircraft noise, no association was observed. The associations did not vary by ER status for any noise source. In analyses using <60 dB as a cutoff, we found HRs of 1.08 (0.99–1.18) for road traffic and 1.19 (0.95–1.49) for railway noise. Conclusions We found weak associations between road and railway noise and breast cancer risk. More high-quality prospective studies are needed, particularly among those exposed to railway and aircraft noise before conclusions regarding noise as a risk factor for breast cancer can be made.
Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts
https://orcid.org/0000-0003-4908-9715
https://orcid.org/0000-0002-3334-9458
https://orcid.org/0000-0002-7580-9547
https://orcid.org/0000-0002-6827-6084
https://orcid.org/0000-0002-9066-8893
https://orcid.org/0000-0001-9519-1935
https://orcid.org/0000-0002-3380-9717
https://orcid.org/0000-0002-1404-9222
https://orcid.org/0000-0002-7815-2632
https://orcid.org/0000-0002-1223-0909
https://orcid.org/0000-0002-9701-1130
https://orcid.org/0000-0003-2354-4652
https://orcid.org/0000-0002-6050-9904
https://orcid.org/0000-0003-4385-2097
https://orcid.org/0000-0001-9332-2241
https://orcid.org/0000-0001-8604-0190
https://orcid.org/0000-0002-4559-4127
https://orcid.org/0000-0001-9594-4140
https://orcid.org/0000-0002-7302-4789
Graphical abstract Display Omitted
Highlights The link between traffic noise and breast cancer was investigated pooling 8 cohorts. This large pooled multi-cohort study included 93,859 women. We found weak associations between road and railway noise and breast cancer risk. The association did not vary by estrogen receptor status. Aircraft noise was not associated with breast cancer incidence.
Abstract Background Environmental noise is an important environmental exposure that can affect health. An association between transportation noise and breast cancer incidence has been suggested, although current evidence is limited. We investigated the pooled association between long-term exposure to transportation noise and breast cancer incidence. Methods Pooled data from eight Nordic cohorts provided a study population of 111,492 women. Road, railway, and aircraft noise were modelled at residential addresses. Breast cancer incidence (all, estrogen receptor (ER) positive, and ER negative) was derived from cancer registries. Hazard ratios (HR) were estimated using Cox Proportional Hazards Models, adjusting main models for sociodemographic and lifestyle variables together with long-term exposure to air pollution. Results A total of 93,859 women were included in the analyses, of whom 5,875 developed breast cancer. The median (5th–95th percentile) 5-year residential road traffic noise was 54.8 (40.0–67.8) dB Lden, and among those exposed, the median railway noise was 51.0 (41.2–65.8) dB Lden. We observed a pooled HR for breast cancer (95 % confidence interval (CI)) of 1.03 (0.99–1.06) per 10 dB increase in 5-year mean exposure to road traffic noise, and 1.03 (95 % CI: 0.96–1.11) for railway noise, after adjustment for lifestyle and sociodemographic covariates. HRs remained unchanged in analyses with further adjustment for PM2.5 and attenuated when adjusted for NO2 (HRs from 1.02 to 1.01), in analyses using the same sample. For aircraft noise, no association was observed. The associations did not vary by ER status for any noise source. In analyses using <60 dB as a cutoff, we found HRs of 1.08 (0.99–1.18) for road traffic and 1.19 (0.95–1.49) for railway noise. Conclusions We found weak associations between road and railway noise and breast cancer risk. More high-quality prospective studies are needed, particularly among those exposed to railway and aircraft noise before conclusions regarding noise as a risk factor for breast cancer can be made.
Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts
https://orcid.org/0000-0003-4908-9715
https://orcid.org/0000-0002-3334-9458
https://orcid.org/0000-0002-7580-9547
https://orcid.org/0000-0002-6827-6084
https://orcid.org/0000-0002-9066-8893
https://orcid.org/0000-0001-9519-1935
https://orcid.org/0000-0002-3380-9717
https://orcid.org/0000-0002-1404-9222
https://orcid.org/0000-0002-7815-2632
https://orcid.org/0000-0002-1223-0909
https://orcid.org/0000-0002-9701-1130
https://orcid.org/0000-0003-2354-4652
https://orcid.org/0000-0002-6050-9904
https://orcid.org/0000-0003-4385-2097
https://orcid.org/0000-0001-9332-2241
https://orcid.org/0000-0001-8604-0190
https://orcid.org/0000-0002-4559-4127
https://orcid.org/0000-0001-9594-4140
https://orcid.org/0000-0002-7302-4789
Graphical abstract Display Omitted
Highlights The link between traffic noise and breast cancer was investigated pooling 8 cohorts. This large pooled multi-cohort study included 93,859 women. We found weak associations between road and railway noise and breast cancer risk. The association did not vary by estrogen receptor status. Aircraft noise was not associated with breast cancer incidence.
Abstract Background Environmental noise is an important environmental exposure that can affect health. An association between transportation noise and breast cancer incidence has been suggested, although current evidence is limited. We investigated the pooled association between long-term exposure to transportation noise and breast cancer incidence. Methods Pooled data from eight Nordic cohorts provided a study population of 111,492 women. Road, railway, and aircraft noise were modelled at residential addresses. Breast cancer incidence (all, estrogen receptor (ER) positive, and ER negative) was derived from cancer registries. Hazard ratios (HR) were estimated using Cox Proportional Hazards Models, adjusting main models for sociodemographic and lifestyle variables together with long-term exposure to air pollution. Results A total of 93,859 women were included in the analyses, of whom 5,875 developed breast cancer. The median (5th–95th percentile) 5-year residential road traffic noise was 54.8 (40.0–67.8) dB Lden, and among those exposed, the median railway noise was 51.0 (41.2–65.8) dB Lden. We observed a pooled HR for breast cancer (95 % confidence interval (CI)) of 1.03 (0.99–1.06) per 10 dB increase in 5-year mean exposure to road traffic noise, and 1.03 (95 % CI: 0.96–1.11) for railway noise, after adjustment for lifestyle and sociodemographic covariates. HRs remained unchanged in analyses with further adjustment for PM2.5 and attenuated when adjusted for NO2 (HRs from 1.02 to 1.01), in analyses using the same sample. For aircraft noise, no association was observed. The associations did not vary by ER status for any noise source. In analyses using <60 dB as a cutoff, we found HRs of 1.08 (0.99–1.18) for road traffic and 1.19 (0.95–1.49) for railway noise. Conclusions We found weak associations between road and railway noise and breast cancer risk. More high-quality prospective studies are needed, particularly among those exposed to railway and aircraft noise before conclusions regarding noise as a risk factor for breast cancer can be made.
Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts
Thacher, Jesse D. (Autor:in) / Oudin, Anna (Autor:in) / Flanagan, Erin (Autor:in) / Mattisson, Kristoffer (Autor:in) / Albin, Maria (Autor:in) / Roswall, Nina (Autor:in) / Pyko, Andrei (Autor:in) / Aasvang, Gunn Marit (Autor:in) / Andersen, Zorana J. (Autor:in) / Borgquist, Signe (Autor:in)
20.07.2023
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Noise , Traffic noise , Railway noise , Aircraft noise , Air pollution , Traffic , Breast cancer , Estrogen receptor , BMI , Body Mass Index , dB , Decibel , DCH , Diet, Cancer and Health , DEN , day, evening, night , DNC , Danish Nurse Cohort , ER , FINRISK , The National FINRISK study , HR , Hazard Ratio , IARC , International Agency for Cancer Research , ICD , International Classification of Diseases , MDCS , Malmö Diet and Cancer Study , NO2 , Nitrogen dioxide , PM , Particulate matter , PM2.5 , Particulate matter with an aerodynamic diameter of ≤2.5 µm , SIXTY , The Stockholm Cohort of 60 -year-olds , SDPP , Stockholm Diabetes Prevention Program , SMC , Swedish Mammography Cohort , SNAC-K , Swedish National Study of Aging and Care in Kungsholmen
| Elsevier | 2023
| DOAJ | 2021