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Method for preparing hydroxyapatite-based composite bioceramic material through in-situ reaction
The invention belongs to the technical field of biomedical biomaterial preparation, and relates to a method for preparing a hydroxyapatite-based composite bioceramic material through an in-situ reaction. According to the method, calcium nitrate tetrahydrate (Ca(NO3)2.4H2O), diammonium hydrogen phosphate ((NH4)2HPO4), aluminum nitrate nonahydrate (Al(NO3)3.9H2O) and ammonium fluoride (NH4F) serve as raw materials, a chemical precipitation method is adopted to prepare fluorine-doped hydroxyapatite and aluminium oxide nanometer composite powder, and then hydroxyapatite-based composite bioceramic is prepared through hot-pressed sintering. The in-situ method is adopted to synthesize the hydroxyapatite and aluminium oxide nanometer composite powder, and uniform distribution of aluminum oxide in a hydroxyapatite matrix is improved; the prepared hydroxyapatite-based composite bioceramic has high biocompatibility and mechanical properties and can be used in the field of repairing or replacing bone tissue of a human body.
Method for preparing hydroxyapatite-based composite bioceramic material through in-situ reaction
The invention belongs to the technical field of biomedical biomaterial preparation, and relates to a method for preparing a hydroxyapatite-based composite bioceramic material through an in-situ reaction. According to the method, calcium nitrate tetrahydrate (Ca(NO3)2.4H2O), diammonium hydrogen phosphate ((NH4)2HPO4), aluminum nitrate nonahydrate (Al(NO3)3.9H2O) and ammonium fluoride (NH4F) serve as raw materials, a chemical precipitation method is adopted to prepare fluorine-doped hydroxyapatite and aluminium oxide nanometer composite powder, and then hydroxyapatite-based composite bioceramic is prepared through hot-pressed sintering. The in-situ method is adopted to synthesize the hydroxyapatite and aluminium oxide nanometer composite powder, and uniform distribution of aluminum oxide in a hydroxyapatite matrix is improved; the prepared hydroxyapatite-based composite bioceramic has high biocompatibility and mechanical properties and can be used in the field of repairing or replacing bone tissue of a human body.
Method for preparing hydroxyapatite-based composite bioceramic material through in-situ reaction
ZHANG XIHUA (Autor:in) / ZHANG CONGYI (Autor:in) / YUAN JIANJUN (Autor:in) / SUN KAI (Autor:in) / DOU JINHE (Autor:in)
21.10.2015
Patent
Elektronische Ressource
Englisch
IPC:
C04B
Kalk
,
LIME
/
A61K
Zubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke
,
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
/
A61L
Verfahren oder Vorrichtungen zum Sterilisieren von Stoffen oder Gegenständen allgemein
,
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
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