Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Zinc-doped calcium phosphate ceramic microspheres with antibacterial function and preparation method of zinc-doped calcium phosphate ceramic microspheres
The invention discloses zinc-doped calcium phosphate ceramic microspheres with an antibacterial function and a preparation method, belongs to the technical field of biomedical materials, and solves the problem that calcium phosphate ceramic in the prior art has no long-acting antibacterial ability. According to the method, zinc is doped into calcium phosphate to form composite microspheres, and the zinc-doped calcium phosphate ceramic particles are obtained after high-temperature sintering. By adopting the method disclosed by the invention, the zinc ions are uniformly doped in the phosphate ceramic matrix, and the zinc ions are gradually released along with the degradation of the phosphate ceramic, so that the calcium phosphate ceramic particles are endowed with long-acting antibacterial activity. The invention accidentally finds that the zinc-doped calcium phosphate ceramic microspheres prepared by the method have a better bone induction effect.
本发明公开了一种具有抗菌功能的锌掺杂磷酸钙陶瓷微球及制备方法，属于生物医用材料技术领域，解决现有技术中磷酸钙陶瓷无长效抗菌能力的问题。本发明方法将锌掺杂到磷酸钙中形成复合微球，经高温烧结后，即得到锌掺杂的磷酸钙陶瓷颗粒。采用本发明方法实现了锌离子在磷酸根陶瓷基体内部均匀的掺杂，锌离子随着磷酸根陶瓷的降解逐渐释放，赋予了磷酸钙陶瓷颗粒的长效的抗菌活性。本发明意外地发现，采用本发明方法制备的锌掺杂磷酸钙陶瓷微球具有更好的骨诱导作用。
Zinc-doped calcium phosphate ceramic microspheres with antibacterial function and preparation method of zinc-doped calcium phosphate ceramic microspheres
The invention discloses zinc-doped calcium phosphate ceramic microspheres with an antibacterial function and a preparation method, belongs to the technical field of biomedical materials, and solves the problem that calcium phosphate ceramic in the prior art has no long-acting antibacterial ability. According to the method, zinc is doped into calcium phosphate to form composite microspheres, and the zinc-doped calcium phosphate ceramic particles are obtained after high-temperature sintering. By adopting the method disclosed by the invention, the zinc ions are uniformly doped in the phosphate ceramic matrix, and the zinc ions are gradually released along with the degradation of the phosphate ceramic, so that the calcium phosphate ceramic particles are endowed with long-acting antibacterial activity. The invention accidentally finds that the zinc-doped calcium phosphate ceramic microspheres prepared by the method have a better bone induction effect.
本发明公开了一种具有抗菌功能的锌掺杂磷酸钙陶瓷微球及制备方法，属于生物医用材料技术领域，解决现有技术中磷酸钙陶瓷无长效抗菌能力的问题。本发明方法将锌掺杂到磷酸钙中形成复合微球，经高温烧结后，即得到锌掺杂的磷酸钙陶瓷颗粒。采用本发明方法实现了锌离子在磷酸根陶瓷基体内部均匀的掺杂，锌离子随着磷酸根陶瓷的降解逐渐释放，赋予了磷酸钙陶瓷颗粒的长效的抗菌活性。本发明意外地发现，采用本发明方法制备的锌掺杂磷酸钙陶瓷微球具有更好的骨诱导作用。
Zinc-doped calcium phosphate ceramic microspheres with antibacterial function and preparation method of zinc-doped calcium phosphate ceramic microspheres
一种具有抗菌功能的锌掺杂磷酸钙陶瓷微球及制备方法
HE TINGHAN (Autor:in) / LIU PUSHEN (Autor:in) / LI XIANGFENG (Autor:in) / LEI NING (Autor:in) / XIAO YUMEI (Autor:in) / ZHANG XINGDONG (Autor:in)
27.05.2022
Patent
Elektronische Ressource
Chinesisch
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