Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Method of detecting fluorescent drug markers in urine
The present disclosure describes a method of detecting a drug marker in a urine sample. The drug markers are fluorophores each of which emits a unique fluorescence spectrum. Accordingly, the method does not detect the drug but rather, the drug marker. The drug marker may include quantum dots which may be functionalized by connecting the quantum dot to a biomolecule. The biomolecule may be cleavable by a peptidase, a protease, or a nuclease to release the drug. Alternatively, the composition may include a liposome carrier. A user who has consumed the drug composition provides a urine sample. The fluorescence spectrometer screens the urine for drug markers based on their unique fluorescent spectra.
Method of detecting fluorescent drug markers in urine
The present disclosure describes a method of detecting a drug marker in a urine sample. The drug markers are fluorophores each of which emits a unique fluorescence spectrum. Accordingly, the method does not detect the drug but rather, the drug marker. The drug marker may include quantum dots which may be functionalized by connecting the quantum dot to a biomolecule. The biomolecule may be cleavable by a peptidase, a protease, or a nuclease to release the drug. Alternatively, the composition may include a liposome carrier. A user who has consumed the drug composition provides a urine sample. The fluorescence spectrometer screens the urine for drug markers based on their unique fluorescent spectra.
Method of detecting fluorescent drug markers in urine
HALL DAVID R (Autor:in) / ROSENBROCK CONRAD (Autor:in) / SWENSON BEN (Autor:in) / HENDRICKS DANIEL (Autor:in) / FOX JOE (Autor:in) / PEARMAN TERRECE (Autor:in)
09.01.2018
Patent
Elektronische Ressource
Englisch
IPC:
G01N
Untersuchen oder Analysieren von Stoffen durch Bestimmen ihrer chemischen oder physikalischen Eigenschaften
,
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
/
A61B
DIAGNOSIS
,
Diagnostik
/
E03D
WATER-CLOSETS OR URINALS WITH FLUSHING DEVICES
,
Wasserklosetts oder Urinale mit Spülvorrichtungen
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