Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Prenatal lignan exposures, pregnancy urine estrogen profiles and birth outcomes
During pregnancy, human exposure to endogenous estrogens and xenoestrogens (such as lignans) may comprehensively impact the gestational maintenance and fetal growth. We measured the concentrations of 5 lignans and the profile of 13 estrogen metabolites (EMs) in the urine samples of 328 pregnant women and examined their associations with birth outcomes. We found significantly positive associations between gestational age and urinary matairesinol (MAT), enterodiol (END) and enterolactone (ENL), as well as 16-hydroxylation pathway EMs. There were consistently positive relationships between END and the 16-hydroxylation pathway EMs. The positive relationships of MAT, END and ENL exposures with the length of gestation were mainly in the low exposure strata of the levels of these EMs. This study reveals that MAT, END and ENL as well as 16-hydroxylation pathway EMs are associated with birth outcomes, and that there are interactive relationships between lignans and 16-hydroxylation pathway EMs with birth outcomes.
Prenatal lignan exposures, pregnancy urine estrogen profiles and birth outcomes
During pregnancy, human exposure to endogenous estrogens and xenoestrogens (such as lignans) may comprehensively impact the gestational maintenance and fetal growth. We measured the concentrations of 5 lignans and the profile of 13 estrogen metabolites (EMs) in the urine samples of 328 pregnant women and examined their associations with birth outcomes. We found significantly positive associations between gestational age and urinary matairesinol (MAT), enterodiol (END) and enterolactone (ENL), as well as 16-hydroxylation pathway EMs. There were consistently positive relationships between END and the 16-hydroxylation pathway EMs. The positive relationships of MAT, END and ENL exposures with the length of gestation were mainly in the low exposure strata of the levels of these EMs. This study reveals that MAT, END and ENL as well as 16-hydroxylation pathway EMs are associated with birth outcomes, and that there are interactive relationships between lignans and 16-hydroxylation pathway EMs with birth outcomes.
Prenatal lignan exposures, pregnancy urine estrogen profiles and birth outcomes
Tang, Rong (Autor:in) / Chen, Minjian / Zhou, Kun / Chen, Daozhen / Yu, Jing / Hu, Weiyue / Song, Ling / Hang, Bo / Wang, Xinru / Xia, Yankai
2015
Aufsatz (Zeitschrift)
Englisch
| DOAJ | 2019
| DOAJ | 2024
Prenatal neonicotinoid insecticides Exposure, oxidative Stress, and birth outcomes
| DOAJ | 2022
Associations of prenatal exposure to phenols with birth outcomes
| Online Contents | 2013
Prenatal exposure to polybrominated diphenyl ethers and birth outcomes
| Online Contents | 2015