Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Molecular docking studies of fused coumarin derivatives as inhibitors of GlcN-6
The biological activity of heterocyclic compounds depends on their structure, the type of hetero atoms in the ring and on the type of substituents present. In this paper, some heterocyclic compounds with coumarin moieties S1-S5 and novobiocin known as coumarin antibiotic were subjected to the molecular docking studies as important tools for drug discovery. Glucosamine-6-phosphate synthase is selected as a suitable target in this study. In silico studies reveal that all synthesized compounds S1-S5 are good inhibitors of GlcN-6 and the docking results are in agreement with in vitro antibacterial evaluation of compounds S1-S5
Molecular docking studies of fused coumarin derivatives as inhibitors of GlcN-6
The biological activity of heterocyclic compounds depends on their structure, the type of hetero atoms in the ring and on the type of substituents present. In this paper, some heterocyclic compounds with coumarin moieties S1-S5 and novobiocin known as coumarin antibiotic were subjected to the molecular docking studies as important tools for drug discovery. Glucosamine-6-phosphate synthase is selected as a suitable target in this study. In silico studies reveal that all synthesized compounds S1-S5 are good inhibitors of GlcN-6 and the docking results are in agreement with in vitro antibacterial evaluation of compounds S1-S5
Molecular docking studies of fused coumarin derivatives as inhibitors of GlcN-6
Govori, Sevdije (Autor:in) / Haziri, Arben / Ademi, Kastriot / Neziraj, Nexhat
2017
Aufsatz (Zeitschrift)
Englisch
USA , Recht , Zeitschrift , Datenverarbeitung
Molecular docking studies of fused coumarin derivatives as inhibitors of GlcN-6
| Taylor & Francis Verlag | 2017
Superior antibacterial activity of GlcN-AuNP-GO by ultraviolet irradiation
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Superior antibacterial activity of GlcN-AuNP-GO by ultraviolet irradiation
| British Library Online Contents | 2016
Superior antibacterial activity of GlcN-AuNP-GO by ultraviolet irradiation
| British Library Online Contents | 2016
| British Library Online Contents | 2011