Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Adsorption Capacity and Biological Activity of Synthetic Zeolites
https://orcid.org/https://orcid.org/0009-0004-3674-6207
https://orcid.org/https://orcid.org/0000-0001-6516-0417
https://orcid.org/https://orcid.org/0000-0002-4042-0718
https://orcid.org/https://orcid.org/0000-0002-5168-2801
The study investigates the physicochemical, porous/textural, and adsorptive properties, as well as the biological activity of BEA, RHO, PAU, and FAU(Y) synthetic zeolites. The adsorption capacity of the zeolites for oxytocin, lysozyme, and albumin—markers of low- and medium-molecular-weight pathological proteins—was measured. The concentration-dependent effects of the zeolites on the viability of human endothelial cells (Ea.hy926) were evaluated. At concentrations of 2.5 to 10 mg/mL, the Y zeolite was found to exhibit no pronounced cytotoxicity. In the presence of the BEA, the cell viability decreased to 80% even at 2.5 mg/mL. The RHO and PAU were shown to have the highest cytotoxicity and significantly inhibit the growth of human cells (down to 23–35%). The study demonstrated that only BEA and Y, among the synthetic zeolites tested, have good biomedical potential due to their high adsorption capacity, low hemolytic activity, and low cytotoxicity.
Adsorption Capacity and Biological Activity of Synthetic Zeolites
https://orcid.org/https://orcid.org/0009-0004-3674-6207
https://orcid.org/https://orcid.org/0000-0001-6516-0417
https://orcid.org/https://orcid.org/0000-0002-4042-0718
https://orcid.org/https://orcid.org/0000-0002-5168-2801
The study investigates the physicochemical, porous/textural, and adsorptive properties, as well as the biological activity of BEA, RHO, PAU, and FAU(Y) synthetic zeolites. The adsorption capacity of the zeolites for oxytocin, lysozyme, and albumin—markers of low- and medium-molecular-weight pathological proteins—was measured. The concentration-dependent effects of the zeolites on the viability of human endothelial cells (Ea.hy926) were evaluated. At concentrations of 2.5 to 10 mg/mL, the Y zeolite was found to exhibit no pronounced cytotoxicity. In the presence of the BEA, the cell viability decreased to 80% even at 2.5 mg/mL. The RHO and PAU were shown to have the highest cytotoxicity and significantly inhibit the growth of human cells (down to 23–35%). The study demonstrated that only BEA and Y, among the synthetic zeolites tested, have good biomedical potential due to their high adsorption capacity, low hemolytic activity, and low cytotoxicity.
Adsorption Capacity and Biological Activity of Synthetic Zeolites
https://orcid.org/https://orcid.org/0009-0004-3674-6207
https://orcid.org/https://orcid.org/0000-0001-6516-0417
https://orcid.org/https://orcid.org/0000-0002-4042-0718
https://orcid.org/https://orcid.org/0000-0002-5168-2801
The study investigates the physicochemical, porous/textural, and adsorptive properties, as well as the biological activity of BEA, RHO, PAU, and FAU(Y) synthetic zeolites. The adsorption capacity of the zeolites for oxytocin, lysozyme, and albumin—markers of low- and medium-molecular-weight pathological proteins—was measured. The concentration-dependent effects of the zeolites on the viability of human endothelial cells (Ea.hy926) were evaluated. At concentrations of 2.5 to 10 mg/mL, the Y zeolite was found to exhibit no pronounced cytotoxicity. In the presence of the BEA, the cell viability decreased to 80% even at 2.5 mg/mL. The RHO and PAU were shown to have the highest cytotoxicity and significantly inhibit the growth of human cells (down to 23–35%). The study demonstrated that only BEA and Y, among the synthetic zeolites tested, have good biomedical potential due to their high adsorption capacity, low hemolytic activity, and low cytotoxicity.
Adsorption Capacity and Biological Activity of Synthetic Zeolites
Pet. Chem.
Ul’yanova, N. Yu. (Autor:in) / Brazovskaya, E. Yu. (Autor:in) / Golubeva, O. Yu. (Autor:in) / Shamova, O. V. (Autor:in)
Petroleum Chemistry ; 63 ; 790-797
01.07.2023
8 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
| TIBKAT | 2008
Biological activity of synthetic leukotriene C
| Elsevier | 1980
Possibilities of coating of glass with synthetic zeolites
| British Library Online Contents | 1993