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Graphene based porous coatings with antibacterial and antithrombogenous function—Materials and design
The studies considered graphene-based biomaterials dedicated for cardiovascular therapy. Reduced graphene oxide flakes were introduced into the porous structure of the polyelectro-lyte based coatings. TEM analysis showed thepresenceofgrapheneflakes arrangedparallelto the substrate surface, firmly connected to the porous coating. Biomaterials were subjectedtoa comprehensive diagnosis ofthe biological and material properties. The material behavior was simulated using finite element method. The coatings were deposited using layer by layer method. Mechanical analysis was done using Berkovich indenter geometry.
They confirmed theoretical FEA based calculations, it was observed the coating stiffness incensement under the influence of introduced particles of graphene.
The endanger of the bacteriology film formation was verified based on the E-coli and Staphylo coccus bacteria. Blood-material interaction was examined in the dynamic flow conditions. Bacteriological analysis showed reduced presence of bacteria after contact with the surface with introduced graphene flakes. Dynamic analyzes on blood showed high activation of the coagulation, strong platelets consumption and a strong immune response. It is caused by sharp edge of the single plane of the graphene flake.
Graphene based porous coatings with antibacterial and antithrombogenous function—Materials and design
The studies considered graphene-based biomaterials dedicated for cardiovascular therapy. Reduced graphene oxide flakes were introduced into the porous structure of the polyelectro-lyte based coatings. TEM analysis showed thepresenceofgrapheneflakes arrangedparallelto the substrate surface, firmly connected to the porous coating. Biomaterials were subjectedtoa comprehensive diagnosis ofthe biological and material properties. The material behavior was simulated using finite element method. The coatings were deposited using layer by layer method. Mechanical analysis was done using Berkovich indenter geometry.
They confirmed theoretical FEA based calculations, it was observed the coating stiffness incensement under the influence of introduced particles of graphene.
The endanger of the bacteriology film formation was verified based on the E-coli and Staphylo coccus bacteria. Blood-material interaction was examined in the dynamic flow conditions. Bacteriological analysis showed reduced presence of bacteria after contact with the surface with introduced graphene flakes. Dynamic analyzes on blood showed high activation of the coagulation, strong platelets consumption and a strong immune response. It is caused by sharp edge of the single plane of the graphene flake.
Graphene based porous coatings with antibacterial and antithrombogenous function—Materials and design
Archiv.Civ.Mech.Eng
Major, R. (Autor:in) / Sanak, M. (Autor:in) / Mzyk, A. (Autor:in) / Lipinska, L. (Autor:in) / Kot, M. (Autor:in) / Lacki, P. (Autor:in) / Bruckert, F. (Autor:in) / Major, B. (Autor:in)
Archives of Civil and Mechanical Engineering ; 14 ; 540-549
01.12.2014
10 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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