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Protists, Unexpected Players in Waterborne Antibiotic Resistance?
The emergence and spread of antibiotic resistance in aquatic environment such as rivers, lakes, and sewage have accelerated microbial threats to human health by promoting the growth of specific waterborne pathogens and transferring them from the ecosystems to humans. Identifying the unexpected drivers of and bottlenecks for human risk assessment of waterborne antibiotic resistance are crucial in understanding and managing the global ARGs transfer. We showed our current understanding of the factors, residual pollutants, bacteriophages, bacterial communities, and the unexpected players’ protists in driving emergence and transfer of waterborne antibiotic resistance. Heterotrophic protists mainly induce waterborne antibiotic resistance because they can accelerate the transfer of ARGs between bacteria and provide optimal environments for antibiotic-resistant pathogens. Current research, however, still cannot provide a comprehensive understanding of the molecular mechanisms of the impacts of protists on waterborne antibiotic resistance. We have, therefore, summarized the key information that is currently missing and discussed the assessment of resistance risk on human health and finally provided some management strategies.
Protists, Unexpected Players in Waterborne Antibiotic Resistance?
The emergence and spread of antibiotic resistance in aquatic environment such as rivers, lakes, and sewage have accelerated microbial threats to human health by promoting the growth of specific waterborne pathogens and transferring them from the ecosystems to humans. Identifying the unexpected drivers of and bottlenecks for human risk assessment of waterborne antibiotic resistance are crucial in understanding and managing the global ARGs transfer. We showed our current understanding of the factors, residual pollutants, bacteriophages, bacterial communities, and the unexpected players’ protists in driving emergence and transfer of waterborne antibiotic resistance. Heterotrophic protists mainly induce waterborne antibiotic resistance because they can accelerate the transfer of ARGs between bacteria and provide optimal environments for antibiotic-resistant pathogens. Current research, however, still cannot provide a comprehensive understanding of the molecular mechanisms of the impacts of protists on waterborne antibiotic resistance. We have, therefore, summarized the key information that is currently missing and discussed the assessment of resistance risk on human health and finally provided some management strategies.
Protists, Unexpected Players in Waterborne Antibiotic Resistance?
Reviews Env.Contamination (formerly:Residue Reviews)
Yu, Yitian (Autor:in) / Zhang, Zhenyan (Autor:in) / Zhang, Qi (Autor:in) / Xu, Nuohan (Autor:in) / Lu, Tao (Autor:in) / Penuelas, Josep (Autor:in) / Sun, Liwei (Autor:in) / Zhu, Yong-Guan (Autor:in) / Qian, Haifeng (Autor:in)
01.12.2022
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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