Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Culturomics and metagenomics: In understanding of environmental resistome
Pharmaceutical residues, mainly antibiotics, have been called “emerging contaminants” in the environment because of their increasing frequency of detection in aquatic and terrestrial systems and their sublethal ecological effects. Most of them are undiscovered. Both human and veterinary pharmaceuticals, including antibiotics, are introduced into the environment via many different routes, including discharges from municipal wastewater treatment plants and land application of animal manure and biosolids to fertilize croplands. To gain a comprehensive understanding of the widespread problem of antibiotic resistance, modern and scientific approaches have been developed to gain knowledge of the entire antibiotic-resistant microbiota of various ecosystems, which is called the resistome. In this review, two omics methods, i.e. culturomics, a new approach, and metagenomics, used to study antibiotic resistance in environmental samples, are described. Moreover, we discuss how both omics methods have become core scientific tools to characterize microbiomes or resistomes, study natural communities and discover new microbes and new antibiotic resistance genes from environments. The combination of the method for get better outcome of both culturomics and metagenomics will significantly advance our understanding of the role of microbes and their specific properties in the environment.
Culturomics and metagenomics: In understanding of environmental resistome
Pharmaceutical residues, mainly antibiotics, have been called “emerging contaminants” in the environment because of their increasing frequency of detection in aquatic and terrestrial systems and their sublethal ecological effects. Most of them are undiscovered. Both human and veterinary pharmaceuticals, including antibiotics, are introduced into the environment via many different routes, including discharges from municipal wastewater treatment plants and land application of animal manure and biosolids to fertilize croplands. To gain a comprehensive understanding of the widespread problem of antibiotic resistance, modern and scientific approaches have been developed to gain knowledge of the entire antibiotic-resistant microbiota of various ecosystems, which is called the resistome. In this review, two omics methods, i.e. culturomics, a new approach, and metagenomics, used to study antibiotic resistance in environmental samples, are described. Moreover, we discuss how both omics methods have become core scientific tools to characterize microbiomes or resistomes, study natural communities and discover new microbes and new antibiotic resistance genes from environments. The combination of the method for get better outcome of both culturomics and metagenomics will significantly advance our understanding of the role of microbes and their specific properties in the environment.
Culturomics and metagenomics: In understanding of environmental resistome
Front. Environ. Sci. Eng.
Nowrotek, Monika (Autor:in) / Jałowiecki, Łukasz (Autor:in) / Harnisz, Monika (Autor:in) / Płaza, Grażyna Anna (Autor:in)
01.06.2019
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Culturomics and metagenomics: In understanding of environmental resistome
| Online Contents | 2019
Environmental antibiotics drives the genetic functions of resistome dynamics
| DOAJ | 2020
The Evolution of Sustainability Ideas in China from 1946 to 2015, Quantified by Culturomics
| DOAJ | 2022
Environmental Metagenomics: The Data Assembly and Data Analysis Perspectives
| Springer Verlag | 2015
Environmental Metagenomics: The Data Assembly and Data Analysis Perspectives
| Springer Verlag | 2015