Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Effects of mercury on glutathione and glutathione-dependent enzymes in hares (Lepus europaeus Pallas)
The aim of this study was to analyze and evaluate risks of long-term exposure to mercury in hares (Lepus europaeus Pallas), with a chemical-analytical approach evaluating median mass fraction of toxic mercury in the hares organs (liver, kidney, muscle and brain). To obtain better insight into possible effects of mercury, the study included screening of the oxidative status after long term exposure to low concentrations of mercury. Hares organs were analyzed for total mercury concentration by AAS. Glutathione and glutathione-dependent enzymes status was also investigated. The median mercury concentrations (wet weight) in the liver, kidney, muscle and brain of the hares ranged from 0.058–0.189, 0.138–0.406, 0.013–0.046 and 0.022–0.102 μg/g respectively. Concentration of the glutathione (GSH), glutathione-peroxidase (GPx), and glutathione-reductase (GR) activity increased with the mercury concentration. However, glutathione S-transferase (GST) and superoxide-dismutase (SOD) activity decreased with the mercury concentration. The results of this study show the impact of environmentally absorbed mercury on the antioxidant status of the examined hares. Further research on long-term exposure to low concentrations of mercury is needed.
Effects of mercury on glutathione and glutathione-dependent enzymes in hares (Lepus europaeus Pallas)
The aim of this study was to analyze and evaluate risks of long-term exposure to mercury in hares (Lepus europaeus Pallas), with a chemical-analytical approach evaluating median mass fraction of toxic mercury in the hares organs (liver, kidney, muscle and brain). To obtain better insight into possible effects of mercury, the study included screening of the oxidative status after long term exposure to low concentrations of mercury. Hares organs were analyzed for total mercury concentration by AAS. Glutathione and glutathione-dependent enzymes status was also investigated. The median mercury concentrations (wet weight) in the liver, kidney, muscle and brain of the hares ranged from 0.058–0.189, 0.138–0.406, 0.013–0.046 and 0.022–0.102 μg/g respectively. Concentration of the glutathione (GSH), glutathione-peroxidase (GPx), and glutathione-reductase (GR) activity increased with the mercury concentration. However, glutathione S-transferase (GST) and superoxide-dismutase (SOD) activity decreased with the mercury concentration. The results of this study show the impact of environmentally absorbed mercury on the antioxidant status of the examined hares. Further research on long-term exposure to low concentrations of mercury is needed.
Effects of mercury on glutathione and glutathione-dependent enzymes in hares (Lepus europaeus Pallas)
Linšak, Željko (Autor:in) / Linšak, Dijana Tomić (Autor:in) / Špirić, Zdravko (Autor:in) / Srebočan, Emil (Autor:in) / Glad, Marin (Autor:in) / Milin, Čedomila (Autor:in)
Journal of Environmental Science and Health, Part A ; 48 ; 1325-1332
19.09.2013
8 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Mercury , enzymes , oxidative stress , hares
Monitoring Urban European Hares (Lepus europaeus Pallas) with Citizen Science and a Thermal Spotter
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