Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Determination of exposure to bitumen and fume from bitumen in the oil industry through determination of urinary 1-hydroxypyrene
This article focuses on a selection of studies in which operators were potentially exposed to to PAHs (polycyclic aromatis hydrocarbon) from bitumen and fume from bitumen. The selected studies involved manufacturing, maintenance of production facilities, and road tanker loading of bitumen. Studies over a number of years in a bitumen manufacturing plant indicated that exposures to PAHs as measured by 1-hydroxypyrene were not statistically significantly different from control values with median values of approximately 0.10 mymol/mmol creatinine. However, occasionally values just over the the internal reference value (up to 0.72 mymol/mol creatinine) were observed. Several studies were performed to investigate the role of dermal exposure to PAH in more detail. In these studies industrial hygienists made detailed work observations to assess semi-quantitatively the extent of inhalatory and dermal exposure. Overal, these studies show that dermal exposure to PAHs may be significant in the total exposure to PAHs and that 1-HOPyrene can be used to assess the efficacy of personal protective equipment. Both inhalatory and dermal exposure from a variety of sources, including bitumen, can readily be assessed by the determination of 1-HOPyrene in urine. Results from biomonitoring indicate that both inhalation and dermal exposure to PAHs during manufacturing and handling of bitumen is negligible.
Determination of exposure to bitumen and fume from bitumen in the oil industry through determination of urinary 1-hydroxypyrene
This article focuses on a selection of studies in which operators were potentially exposed to to PAHs (polycyclic aromatis hydrocarbon) from bitumen and fume from bitumen. The selected studies involved manufacturing, maintenance of production facilities, and road tanker loading of bitumen. Studies over a number of years in a bitumen manufacturing plant indicated that exposures to PAHs as measured by 1-hydroxypyrene were not statistically significantly different from control values with median values of approximately 0.10 mymol/mmol creatinine. However, occasionally values just over the the internal reference value (up to 0.72 mymol/mol creatinine) were observed. Several studies were performed to investigate the role of dermal exposure to PAH in more detail. In these studies industrial hygienists made detailed work observations to assess semi-quantitatively the extent of inhalatory and dermal exposure. Overal, these studies show that dermal exposure to PAHs may be significant in the total exposure to PAHs and that 1-HOPyrene can be used to assess the efficacy of personal protective equipment. Both inhalatory and dermal exposure from a variety of sources, including bitumen, can readily be assessed by the determination of 1-HOPyrene in urine. Results from biomonitoring indicate that both inhalation and dermal exposure to PAHs during manufacturing and handling of bitumen is negligible.
Determination of exposure to bitumen and fume from bitumen in the oil industry through determination of urinary 1-hydroxypyrene
Ermittlung der Bitumen- und Bitumendampfexposition in der Erdölindustrie durch Bestimmung von 1-Hydroxypyren im Urin
Boogaard, Peter J. (Autor:in)
2007
7 Seiten, 2 Bilder, 1 Tabelle, 28 Quellen
Aufsatz (Konferenz)
Englisch
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