Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Mesenchymal Stem Cells‐Involved Strategies for Rheumatoid Arthritis Therapy
https://orcid.org/0009-0009-6905-4473
https://orcid.org/0000-0002-5347-3499
https://orcid.org/0000-0002-0146-8532
https://orcid.org/0000-0002-7141-5794
https://orcid.org/0000-0002-3352-9715
https://orcid.org/0000-0002-5232-8863
AbstractRheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints and bone destruction. Because of systemic administration and poor targeting, traditional anti‐rheumatic drugs have unsatisfactory treatment efficacy and strong side effects, including myelosuppression, liver or kidney function damage, and malignant tumors. Consequently, mesenchymal stem cells (MSCs)‐involved therapy is proposed for RA therapy as a benefit of their immunosuppressive and tissue‐repairing effects. This review summarizes the progress of MSCs‐involved RA therapy through suppressing inflammation and promoting tissue regeneration and predicts their potential clinical application.
Mesenchymal Stem Cells‐Involved Strategies for Rheumatoid Arthritis Therapy
https://orcid.org/0009-0009-6905-4473
https://orcid.org/0000-0002-5347-3499
https://orcid.org/0000-0002-0146-8532
https://orcid.org/0000-0002-7141-5794
https://orcid.org/0000-0002-3352-9715
https://orcid.org/0000-0002-5232-8863
AbstractRheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints and bone destruction. Because of systemic administration and poor targeting, traditional anti‐rheumatic drugs have unsatisfactory treatment efficacy and strong side effects, including myelosuppression, liver or kidney function damage, and malignant tumors. Consequently, mesenchymal stem cells (MSCs)‐involved therapy is proposed for RA therapy as a benefit of their immunosuppressive and tissue‐repairing effects. This review summarizes the progress of MSCs‐involved RA therapy through suppressing inflammation and promoting tissue regeneration and predicts their potential clinical application.
Mesenchymal Stem Cells‐Involved Strategies for Rheumatoid Arthritis Therapy
https://orcid.org/0009-0009-6905-4473
https://orcid.org/0000-0002-5347-3499
https://orcid.org/0000-0002-0146-8532
https://orcid.org/0000-0002-7141-5794
https://orcid.org/0000-0002-3352-9715
https://orcid.org/0000-0002-5232-8863
AbstractRheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints and bone destruction. Because of systemic administration and poor targeting, traditional anti‐rheumatic drugs have unsatisfactory treatment efficacy and strong side effects, including myelosuppression, liver or kidney function damage, and malignant tumors. Consequently, mesenchymal stem cells (MSCs)‐involved therapy is proposed for RA therapy as a benefit of their immunosuppressive and tissue‐repairing effects. This review summarizes the progress of MSCs‐involved RA therapy through suppressing inflammation and promoting tissue regeneration and predicts their potential clinical application.
Mesenchymal Stem Cells‐Involved Strategies for Rheumatoid Arthritis Therapy
Advanced Science
Li, Chaoyang (Autor:in) / Sun, Yifu (Autor:in) / Xu, Weiguo (Autor:in) / Chang, Fei (Autor:in) / Wang, Yinan (Autor:in) / Ding, Jianxun (Autor:in)
Advanced Science ; 11
01.06.2024
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Mesenchymal Stem Cells‐Involved Strategies for Rheumatoid Arthritis Therapy
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