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Detection limits of organic contaminants in drinking water
Better control of MDL determination will substantially reduce interlaboratory variation.
This article examines some of the experimental variables that can contribute to the observed variability in laboratory performance. The examples provided suggest that method detection limits (MDLs) would be more uniform among laboratories if (1) uniform spike concentrations were used in MDL determination; (2) analytical methods were more uniform as to procedures, reagents, and materials; and (3) tighter guidelines were established for conducting MDL experiments and handling MDL data. The pooling of data from multiple spike levels (or any other means to increase sample size) minimizes random error in MDL determination. Improved control in MDL determination would lead to better information on laboratory capabilities, and this in turn would improve the technical basis for reporting limits, trigger levels, and water quality standards.
Detection limits of organic contaminants in drinking water
Better control of MDL determination will substantially reduce interlaboratory variation.
This article examines some of the experimental variables that can contribute to the observed variability in laboratory performance. The examples provided suggest that method detection limits (MDLs) would be more uniform among laboratories if (1) uniform spike concentrations were used in MDL determination; (2) analytical methods were more uniform as to procedures, reagents, and materials; and (3) tighter guidelines were established for conducting MDL experiments and handling MDL data. The pooling of data from multiple spike levels (or any other means to increase sample size) minimizes random error in MDL determination. Improved control in MDL determination would lead to better information on laboratory capabilities, and this in turn would improve the technical basis for reporting limits, trigger levels, and water quality standards.
Detection limits of organic contaminants in drinking water
Draper, William M. (Autor:in) / Dhoot, Jagdev S. (Autor:in) / Dhaliwal, Joginder S. (Autor:in) / Remoy, John W. (Autor:in) / Perera, S. Kusum (Autor:in) / Baumann, Frank J. (Autor:in)
Journal ‐ American Water Works Association ; 90 ; 82-90
01.06.1998
9 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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