Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
10.1002/tox.20139.abs
Phenol and aniline are toxic to animals. The purpose of the present study was to examine the expression of glutathione transferase D mRNA in fruit flies altered by long‐term exposure to phenol and aniline. Changes in the amount of mRNA were measured by a semiquantitative reverse‐transcription polymerase chain reaction assay. The level of each glutathione transferase D mRNA expressed in the phenol‐treated and aniline‐treated strains of adult fruit flies differed after chemical treatment. Aniline was more potent than phenol in suppressing the expression of cytosolic glutathione transferase D mRNA. Aniline reduced the level of glutathione transferase mRNA expressed in the aniline‐treated strain to less than a 0.5 fraction as compared to that measured in the wild‐type strain. But phenol was only able to suppress the GstD7 and GstD4 mRNAs expressed in the phenol‐treated strain. Neither aniline nor phenol reduced the expression of microsomal glutathione transferase mRNA in fruit flies. © 2005 Wiley Periodicals, Inc. Environ Toxicol 20: 507–512, 2005.
10.1002/tox.20139.abs
Phenol and aniline are toxic to animals. The purpose of the present study was to examine the expression of glutathione transferase D mRNA in fruit flies altered by long‐term exposure to phenol and aniline. Changes in the amount of mRNA were measured by a semiquantitative reverse‐transcription polymerase chain reaction assay. The level of each glutathione transferase D mRNA expressed in the phenol‐treated and aniline‐treated strains of adult fruit flies differed after chemical treatment. Aniline was more potent than phenol in suppressing the expression of cytosolic glutathione transferase D mRNA. Aniline reduced the level of glutathione transferase mRNA expressed in the aniline‐treated strain to less than a 0.5 fraction as compared to that measured in the wild‐type strain. But phenol was only able to suppress the GstD7 and GstD4 mRNAs expressed in the phenol‐treated strain. Neither aniline nor phenol reduced the expression of microsomal glutathione transferase mRNA in fruit flies. © 2005 Wiley Periodicals, Inc. Environ Toxicol 20: 507–512, 2005.
Reducing the expression of glutathione transferase D mRNA in Drosophila melanogaster exposed to phenol and aniline
Environmental Toxicology ; 20 ; 507-512
01.10.2005
6 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Expression of carotenoid pigments of haloarchaeal cultures exposed to aniline
| Online Contents | 2005