Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Effects of chlorpyrifos on the metabolome of the freshwater carp, Cyprinus Carpio
This study investigated the effects of waterborne chlorpyrifos with concentrations of 1 and 100 µg/L for L and H‐groups, respectively, on metabolome profiles of carp plasma using 1H‐NMR. Principal component analysis suggests that chlorpyrifos exposure firstly affected in L and H‐groups on day 2 or 4, and followed a second effect in both exposure groups on day 14. Levels of metabolites related to the energy production in the body, such as glucose, glycerol, valine, leucine, isoleucine, lactate, alanine, 3‐D‐hydroxybutyrates and acetoacetate, significantly changed by exposures of chlorpyrifos. Those results suggest that energy production was severely affected in carp. The exposure could also be highly elevated ammonia levels especially in H‐group due to severe convulsion in muscle caused by the inhibition of acetylcholinesterase activity. © 2013 Wiley Periodicals, Inc. Environ Toxicol 30: 253–260, 2015.
Effects of chlorpyrifos on the metabolome of the freshwater carp, Cyprinus Carpio
This study investigated the effects of waterborne chlorpyrifos with concentrations of 1 and 100 µg/L for L and H‐groups, respectively, on metabolome profiles of carp plasma using 1H‐NMR. Principal component analysis suggests that chlorpyrifos exposure firstly affected in L and H‐groups on day 2 or 4, and followed a second effect in both exposure groups on day 14. Levels of metabolites related to the energy production in the body, such as glucose, glycerol, valine, leucine, isoleucine, lactate, alanine, 3‐D‐hydroxybutyrates and acetoacetate, significantly changed by exposures of chlorpyrifos. Those results suggest that energy production was severely affected in carp. The exposure could also be highly elevated ammonia levels especially in H‐group due to severe convulsion in muscle caused by the inhibition of acetylcholinesterase activity. © 2013 Wiley Periodicals, Inc. Environ Toxicol 30: 253–260, 2015.
Effects of chlorpyrifos on the metabolome of the freshwater carp, Cyprinus Carpio
Kokushi, Emiko (Autor:in) / Uno, Seiichi (Autor:in) / Pal, Sandipan (Autor:in) / Koyama, Jiro (Autor:in)
Environmental Toxicology ; 30 ; 253-260
01.03.2015
8 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Effects of chlorpyrifos on the metabolome of the freshwater carp, Cyprinus Carpio
| Online Contents | 2015
| DOAJ | 2020
Immunosupresive effects of cyanotoxins on carp (Cyprinus carpio) after peroral application
| British Library Conference Proceedings | 1997
Acute Toxicity of Heavy Metals to Common Carp (Cyprinus carpio)
| Online Contents | 1995