Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Descriptive and mechanistic toxicity of conazole fungicides using the model test alga Dunaliella tertiolecta (chlorophyceae)
Conazole fungicides are commonly used to prevent fungal growth on turf grass and agricultural crops. As many of these sites are adjacent to coastal waterways and estuaries, there exists the potential for nontarget effects of runoff on marine organisms. This study reports 96 h EC50 values for four selected conazole fungicides (triadimefon = 5.98 mg/L; triadimenol = 5.51 mg/L; propiconazole = 2.33 mg/L; hexaconazole = 0.91 mg/L) to the model test alga Dunaliella tertiolecta. We further investigated possible mechanisms of toxicity by examining sublethal effects of exposure on cell morphology, osmoregulatory function, and lipid composition. These mechanistic studies revealed that conazole exposure does not inhibit synthesis of the cell's glycerol osmolyte, but does result in an overall increase in cellular volume and total lipid content. Both fungi and chlorophytes rely on ergosterol to maintain membrane structure and fluidity, and we provide evidence that the sterol‐inhibiting conazoles may interfere with ergosterol biosynthesis in the cell membrane of Dunaliella. These findings suggest that green algae may be especially susceptible to nontarget effects of sterol‐inhibiting fungicides in marine systems. Published 2009 by Wiley Periodicals, Inc. Environ Toxicol 2010
Descriptive and mechanistic toxicity of conazole fungicides using the model test alga Dunaliella tertiolecta (chlorophyceae)
Conazole fungicides are commonly used to prevent fungal growth on turf grass and agricultural crops. As many of these sites are adjacent to coastal waterways and estuaries, there exists the potential for nontarget effects of runoff on marine organisms. This study reports 96 h EC50 values for four selected conazole fungicides (triadimefon = 5.98 mg/L; triadimenol = 5.51 mg/L; propiconazole = 2.33 mg/L; hexaconazole = 0.91 mg/L) to the model test alga Dunaliella tertiolecta. We further investigated possible mechanisms of toxicity by examining sublethal effects of exposure on cell morphology, osmoregulatory function, and lipid composition. These mechanistic studies revealed that conazole exposure does not inhibit synthesis of the cell's glycerol osmolyte, but does result in an overall increase in cellular volume and total lipid content. Both fungi and chlorophytes rely on ergosterol to maintain membrane structure and fluidity, and we provide evidence that the sterol‐inhibiting conazoles may interfere with ergosterol biosynthesis in the cell membrane of Dunaliella. These findings suggest that green algae may be especially susceptible to nontarget effects of sterol‐inhibiting fungicides in marine systems. Published 2009 by Wiley Periodicals, Inc. Environ Toxicol 2010
Descriptive and mechanistic toxicity of conazole fungicides using the model test alga Dunaliella tertiolecta (chlorophyceae)
Baird, Thomas D. (Autor:in) / DeLorenzo, Marie E. (Autor:in)
Environmental Toxicology ; 25 ; 213-220
01.06.2010
8 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
| British Library Conference Proceedings | 2010
Preliminary Toxicity Tests Using the Green Alga, Ankistrodesmus falcatus
| Online Contents | 1997