Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Breast Tumor Diagnosis Based on Molecular Learning Vector Quantization Neural Networks
DNA nanotechnology plays a crucial role in precise cancer medicine. Currently, molecular logic circuits are applied to detect tumor‐specific biomarkers and control the release of therapeutic drugs. However, these systems lack self‐learning capabilities for intelligent diagnostics in biological samples, and their data processing capabilities are limited. Here, a molecular learning vector quantization neural network (LVQNN) model based on DNA strand displacement (DSD) technology for breast tumor diagnosis is developed. Compared to previous work, the molecular LVQNN boasts powerful computing abilities, handling high‐dimensional data for intelligent cancer diagnosis. To verify the feasibility and versatility of the network, two distinct typical datasets are selected: one from a single source with cell morphology data from 569 cases, and a more extensive one spanning different populations and ages, with miRNA gene expression data from 1881 cases. By using the molecular LVQNN, diagnostic experiments are conducted on 50 and 120 public individuals from these two datasets, respectively, achieving accuracy rates of 94% and 97.5%. This study demonstrates that the LVQNN model exhibits significant advantages in breast cancer diagnosis and enhances diagnostic accuracy while introducing new approaches for intelligent cancer diagnosis, anticipated to bring significant breakthroughs and application prospects to precise cancer medicine.
Breast Tumor Diagnosis Based on Molecular Learning Vector Quantization Neural Networks
DNA nanotechnology plays a crucial role in precise cancer medicine. Currently, molecular logic circuits are applied to detect tumor‐specific biomarkers and control the release of therapeutic drugs. However, these systems lack self‐learning capabilities for intelligent diagnostics in biological samples, and their data processing capabilities are limited. Here, a molecular learning vector quantization neural network (LVQNN) model based on DNA strand displacement (DSD) technology for breast tumor diagnosis is developed. Compared to previous work, the molecular LVQNN boasts powerful computing abilities, handling high‐dimensional data for intelligent cancer diagnosis. To verify the feasibility and versatility of the network, two distinct typical datasets are selected: one from a single source with cell morphology data from 569 cases, and a more extensive one spanning different populations and ages, with miRNA gene expression data from 1881 cases. By using the molecular LVQNN, diagnostic experiments are conducted on 50 and 120 public individuals from these two datasets, respectively, achieving accuracy rates of 94% and 97.5%. This study demonstrates that the LVQNN model exhibits significant advantages in breast cancer diagnosis and enhances diagnostic accuracy while introducing new approaches for intelligent cancer diagnosis, anticipated to bring significant breakthroughs and application prospects to precise cancer medicine.
Breast Tumor Diagnosis Based on Molecular Learning Vector Quantization Neural Networks
Huang, Chun (Autor:in) / Shao, Jiaying (Autor:in) / Peng, Baolei (Autor:in) / Guo, Qingshuang (Autor:in) / Li, Panlong (Autor:in) / Sun, Junwei (Autor:in) / Wang, Yanfeng (Autor:in)
Advanced Science ; 11
01.11.2024
12 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
Breast Tumor Diagnosis Based on Molecular Learning Vector Quantization Neural Networks
| Wiley | 2024
Noise Fuzzy Learning Vector Quantization
| British Library Online Contents | 2010
Force Control of Hybrid Actuator Using Learning Vector Quantization Neural Network
| British Library Online Contents | 2006
Intelligent Switching Control of Pneumatic Cylinders by Learning Vector Quantization Neural Network
| British Library Online Contents | 2005
Fuzzy learning vector quantization for hyperspectral coastal vegetation classification
| Online Contents | 2006