Antimicrobial Electrospun Materials: Fid-Bau Portal

Antimicrobial Electrospun Materials

Ambekar, Rushikesh S. / Kandasubramanian, Balasubramanian

The human body needs to be protected from invaders in the world like microbes as WHO data shows that 17 million people die every year due to infectious diseases, source of these infectious diseases are microbes such as bacteria, fungi, protozoa, and viruses. In the last 20 years, 30 new diseases were discovered by researchers. Bacteria are the most common microbe which attacks the human body; therefore, protection from such life‐threatening microorganism is extremely necessary. Anti‐microbial drugs were discovered long back but their sustained dose only help in antibacterial effects otherwise burst release of the drug can cause side effects on the human body. To acquire sustained release drug embedded biopolymer system are most commonly practiced in this way drug release can be tuned with the degradation of biopolymers. There are many techniques for fabrication of drug/polymer system but to achieve higher efficiency rate higher surface area is required, therefore, nanotechnology utilizes for designing such high surface area materials such as nanofibers. Nanofibers can be fabricated via melt spinning, pressurized gyration, phase separation and electrospinning, out of which electrospinning is most popular due to enormous surface area, tunable fiber diameter, highly biocompatible, cost‐effectiveness. In the present chapter, we have discussed recent advances in drug embedded biodegradable electrospun nanofibers as well as non‐biodegradable electrospun nanofibers for anti‐bacterial applications.