Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Numerical Analysis of the Die Filling Process Within a Pharmaceutical Tableting Machine
One of the main benefits of numerical simulations is the ability to shed light on the underlying physics in unit operations. This advantage was exploited in this work to study the die filling process in a lab‐scale pharmaceutical rotary tablet press. The die filling process with emphasis on mass holdup, mass flow rate, tablet mass, and API content in the dies is described in detail. Eventually a design of experiments provides a clear picture on the influence of process conditions and material properties on the tablet mass to improve the process understanding.
Numerical Analysis of the Die Filling Process Within a Pharmaceutical Tableting Machine
One of the main benefits of numerical simulations is the ability to shed light on the underlying physics in unit operations. This advantage was exploited in this work to study the die filling process in a lab‐scale pharmaceutical rotary tablet press. The die filling process with emphasis on mass holdup, mass flow rate, tablet mass, and API content in the dies is described in detail. Eventually a design of experiments provides a clear picture on the influence of process conditions and material properties on the tablet mass to improve the process understanding.
Numerical Analysis of the Die Filling Process Within a Pharmaceutical Tableting Machine
Hildebrandt, Claudia (Autor:in) / Gopireddy, Srikanth R. (Autor:in) / Scherließ, Regina (Autor:in) / Urbanetz, Nora (Autor:in)
Chemie Ingenieur Technik ; 90 ; 483-492
01.04.2018
10 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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