Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Ion‐Exchange Adsorption of Proteins: Experiments and Molecular Dynamics Simulations
The adsorption of serum albumin and hemoglobin onto Q Sepharose FF was investigated, where the single and binary adsorption were considered. Both experiments and molecular dynamics simulations have been performed to study the adsorption from macroscopic and microscopic points of view. The steric mass‐action model was applied to describe the single adsorption isotherms and to predict the binary isotherms. The results of the experiments and simulations were connected and compared by two parameters of the steric mass‐action model. Both results present a preferential adsorption of serum albumin.
Ion‐Exchange Adsorption of Proteins: Experiments and Molecular Dynamics Simulations
The adsorption of serum albumin and hemoglobin onto Q Sepharose FF was investigated, where the single and binary adsorption were considered. Both experiments and molecular dynamics simulations have been performed to study the adsorption from macroscopic and microscopic points of view. The steric mass‐action model was applied to describe the single adsorption isotherms and to predict the binary isotherms. The results of the experiments and simulations were connected and compared by two parameters of the steric mass‐action model. Both results present a preferential adsorption of serum albumin.
Ion‐Exchange Adsorption of Proteins: Experiments and Molecular Dynamics Simulations
Liang, Juan (Autor:in) / Fieg, Georg (Autor:in) / Jakobtorweihen, Sven (Autor:in)
Chemie Ingenieur Technik ; 87 ; 903-909
01.07.2015
7 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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