Rumah Sakit Umum Daerah (RSD) Mangusada sebagai penyedia fasilitas kesehatan tentunya menghasilkan limbah cair dalam setiap kegiatan operasionalnya. Air limbah pada Instalasi Pengolahan Air Limbah (IPAL) RSD Mangusada mengandung kandungan Biological Oxygen Demand (BOD5), Chemical Oxygen Demand (COD), Total Suspended Solid (TSS), amonia, total coliform, Total Dissolved Solid (TDS), detergen, minyak dan lemak. Penelitian ini bertujuan untuk mengevaluasi kinerja dari IPAL serta mengetahui kandungan pada air limbah setelah diolah oleh IPAL RSD Mangusada sesuai dengan baku mutu acuan dari Peraturan Gubernur Bali No. 16 Tahun 2016 dan Peraturan Menteri Lingkungan Hidup dan Kehutanan Republik Indonesia Nomor: P.68/ Menlhk/Setjen/ Kum.1/8/2016. Sistem pengolahan air limbah di RSD Mangusada menggunakan sistem biologis. Data yang digunakan dalam analisis adalah data sekunder, yaitu data Bed Occupation Rate (BOR) bulan Juni 2020, jumlah tempat tidur total, debit rata-rata outlet bulan Juni 2020 serta parameter kualitas dan kuantitas air limbah di inlet dan outlet IPAL bulan Januari 2020 hingga Juli 2020. Berdasarkan hasil pengujian kualitas dan kuantitas air limbah pada outlet IPAL RSD Mangusada, kandungan air limbah yang terdapat pada outlet IPAL sesuai dengan standar peraturan baku mutu acuan. Selain itu, efektivitas dari efisiensi IPAL RSD Mangusada berhasil menurunkan kandungan amonia 92,35%, BOD5 64,03%, COD 63,97%, TSS 67,03%, minyak dan lemak 64,64%, total coliform 76,84%, dan detergen sebesar 76,25%. Tetapi efisiensi dari IPAL RSD Mangusada kurang baik dalam penurunan kandungan TDS sebesar -3,92%. ; The Mangusada Regional General Hospital (RSD) as a provider of health facilities certainly produces liquid waste in every operational activity. Wastewater in the Wastewater Treatment Installation (WWTI) RSD Mangusada contains Biological Oxygen Demand (BOD5), Chemical Oxygen Demand (COD), Total Suspended Solid (TSS), ammonia, total coliform, Total Dissolved Solid (TDS), detergent, oil and fat. This study aims to evaluate the performance of the WWTI as well as to determine the content in the wastewater after being treated by the IPAL RSD Mangusada according to the reference quality standards of the Governor of Bali Regulation No.16/2016 and Regulation of the Minister of Environment and Forestry of the Republic of Indonesia Number: P.68/Menlhk/Setjen/Kum.1/8/2016. The wastewater treatment system at RSD Mangusada uses a biological system. The data used in the analysis are secondary data, namely the Bed Occupation Rate (BOR) data in June 2020, the total number of beds, the average discharge of outlets in June 2020 and parameters of the quality and quantity of wastewater in the inlet and outlet of WWTI from January 2020 to July 2020. Based on the results of testing the quality and quantity of wastewater at the WWTI of RSD Mangusada outlet, the content of waste water in the outlet of WWTI is in accordance with the regulatory standards for the reference quality standards. In addition, the effectiveness of the efficiency of the WWTI at RSD Mangusada succeeded in reducing the ammonia content of 92.35%, BOD5 64.03%, COD 63.97%, TSS 67.03%, oil and fat 64.64%, total coliform 76.84%. , and detergent at 76.25%. But the efficiency of the WWTI of RSD Mangusada was not good enough in reducing the TDS content of -3.92%.