When lateral loads are applied on a pile, lateral deflection of the pile depends on the soil resistance and the soil resistance in turn depends on the pile deflection and this dependence is known as soil-pile interaction. Dynamic soil-pile interaction analysis has become an important field in civil engineering over the past years. Several major earthquakes that caused damage to buildings and other infrastructure have brought a lot of attention to response of pile foundations subjected to dynamic loading. When a pile is subjected to a seismic excitation, deformation of the pile is caused by the movement of surrounding soil with the passage of seismic waves (kinematic interaction) as well as the inertial forces applied by the superstructure due to its oscillation during the excitation (inertial interaction). But, in actual engineering practice, pile responses are calculated using the pseudo-static approach which considers only the inertial interaction effects, which essentially neglects kinematic interaction effects. The field observations of pile failures after seismic events have highlighted the importance of incorporating kinematic effects in the design process. Hence some codes such as Euro code states those kinematic effects should be considered during the pile design process. However, still there is no definite method to techniques to analyses pile foundations for seismic loads considering both kinematic and inertial effects. In this research Finite Element Method (FEM) is used as the analyzing tool over the most widely used “Beam-On-Foundation” method, due to the reliability of FEM in simulating and analyzing of soil-pile interaction problems. First the techniques were determined and incorporated in a three dimensional model developed using the general purpose finite element software ABAQUS to simulate the soil-pile system during a seismic excitation. The model was then extended to model the deep piles in multilayered soil profiles. For the investigation an actual soil profile was obtained from a site investigation. This consists of a deep marine sediment layer at the top of the profile and underlying soil layers with increasing stiffness and the scaled El-Centro were given to the soil-pile system. Also analyses were carried out varying the uppermost soft soil layer thickness to investigate the effect of soft soil layer thickness on pile behavior. Finally a parametric study was carried using soil profiles; with a deep soft soil layer. The analysis carried out show that the developed model has the capability of capturing important pile behavior under seismic excitations such as response due to kinematic and inertial interaction effects, effect of soil stiffness on pile behavior, deflection patterns and permanent deformations. It highlights that, input to the superstructure in seismic analysis should be modified depending on the soil-pile interaction effects, rather than using the original motion at the base of the structure which is the normal engineering practice. Moreover, analysis results show that pile behavior is unique and depends on many factors such as the nature of the soil profile it is embedded, soft layer thickness and properties of input motions. Furthermore, the developed model provides reliable techniques to simulate soil-pile interaction which can be used in actual engineering practice and also can be extended for further research purposes. The analysis carried out show that the developed model has the capability of capturing important pile behavior under seismic excitations such as response due to kinematic and inertial interaction effects, effect of soil stiffness on pile behavior, deflection patterns and permanent deformations. It highlights that, input to the superstructure in seismic analysis should be modified depending on the soil-pile interaction effects, rather than using the original motion at the base of the structure which is the normal engineering practice. Moreover, analysis results show that pile behavior is unique and depends on many factors such as the nature of the soil profile it is embedded, soft layer thickness and properties of input motions. Furthermore, the developed model provides reliable techniques to simulate soil-pile interaction which can be used in actual engineering practice and also can be extended for further research purposes.