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Correlation of left atrial anatomy to the success of atrial fibrillation catheter ablation
Atrial fibrillation is the most common supraventricular arrhythmia in the world, affecting around 1-2% in developed countries. It causes 20-30% of all strokes and 20-30% of patients may develop left ventricular dysfunction. The focus starts in most cases from the Ostia of the pulmonary veins. This area is the target for catheter ablation, an invasive and curative procedure. After multiple ablations, the success rate is around 80%. Data as to which parameters of the left atrium and the patient correlate with the success of the procedure or the recurrence of the arrhythmia is lacking. For better patient selection this study tries to see if such a correlation exists. 100 patients with medication-refractory and symptomatic atrial fibrillation, presenting for the first ablation in the years 2014 and 2015 were evaluated in this retrospective study for their basic characteristics and their left atrial characteristics measured on a 3D-model of the heart constructed from a contrast-enhanced computed tomography. The success rate of pulmonary venous isolation showed a success rate of 83% after six months and around 40% after three years after a single procedure. The basic parameters of the patients did not show any correlation with this long-term outcome. The pulmonary veins showed the same relation to each other as already seen in other studies. The superior veins were larger than their inferior partners and the right side had generally larger veins than the left side. Two of the variations of the pulmonary veins showed a promising trend, but due to the low number of cases, a definite relation cannot be given. The presence of a left common trunk indicates a lower recurrence rate in the long term, and the common left ostium has a lower recurrence rate in the short-term (around 750 days). But a clear correlation between the anatomical variations with the success of the ablation procedure was not visible. An association between the size of the left atrial auricle and the recurrence of atrial fibrillation post-ablation was ...
Correlation of left atrial anatomy to the success of atrial fibrillation catheter ablation
Atrial fibrillation is the most common supraventricular arrhythmia in the world, affecting around 1-2% in developed countries. It causes 20-30% of all strokes and 20-30% of patients may develop left ventricular dysfunction. The focus starts in most cases from the Ostia of the pulmonary veins. This area is the target for catheter ablation, an invasive and curative procedure. After multiple ablations, the success rate is around 80%. Data as to which parameters of the left atrium and the patient correlate with the success of the procedure or the recurrence of the arrhythmia is lacking. For better patient selection this study tries to see if such a correlation exists. 100 patients with medication-refractory and symptomatic atrial fibrillation, presenting for the first ablation in the years 2014 and 2015 were evaluated in this retrospective study for their basic characteristics and their left atrial characteristics measured on a 3D-model of the heart constructed from a contrast-enhanced computed tomography. The success rate of pulmonary venous isolation showed a success rate of 83% after six months and around 40% after three years after a single procedure. The basic parameters of the patients did not show any correlation with this long-term outcome. The pulmonary veins showed the same relation to each other as already seen in other studies. The superior veins were larger than their inferior partners and the right side had generally larger veins than the left side. Two of the variations of the pulmonary veins showed a promising trend, but due to the low number of cases, a definite relation cannot be given. The presence of a left common trunk indicates a lower recurrence rate in the long term, and the common left ostium has a lower recurrence rate in the short-term (around 750 days). But a clear correlation between the anatomical variations with the success of the ablation procedure was not visible. An association between the size of the left atrial auricle and the recurrence of atrial fibrillation post-ablation was ...
Correlation of left atrial anatomy to the success of atrial fibrillation catheter ablation
Roosta Azad, Mahan (author) / Wakili Noduschan, Reza
2023-04-06
Theses
Electronic Resource
English
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