A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
Electrophoretic Deposition of Laser-generated Platinum- and Platinum-Alloy Nanoparticles onto Neural Electrode Surfaces
Platinum-based neural electrodes are used for implantation in the brain for recording neuronal activity and for acute or chronic neural stimulation, such as deep brain stimulation (DBS). For diseases like Parkinson’s, epilepsy, depression, deafness, spinal cord injuries, blindness, advanced tremors, etc., there is no complete cure. Therefore, to reduce the severity of the symptoms and to improve the patient’s quality of life, DBS is often performed. Although neural electrodes have been clinically used for a long time now, there are some drawbacks such as the increase in electrode impedance (Z) due to gliosis formation that reduces the efficacy of the electrodes to record or stimulate the neurons. Due to increasing Z, higher currents are required for better stimulation, which consequently reduces the battery life of the pulse generator. To eliminate these challenges faced by neurosurgeons, research has been carried out by modifying the surface topography using various methods to increase the electrochemical surface area (ECSA) and thereby reducing the Z. Various surface modification techniques have been employed for this purpose: chemical modifications, laser patterning, electrodeposition, vapor deposition, self-assembly, etc. One of the rising techniques is the electrophoretic deposition (EPD) of laser-generated ligand-free nanoparticles (NPs) onto platinum (Pt) electrode surfaces. It is one of the most versatile and simple methods without requiring complex equipment or processing tools. By the application of external electric fields, the colloidal NPs dispersed in water are subjected to a movement towards the oppositely charged electrode, on which the deposition takes place. The deposition output can be easily modified by simply adjusting the process parameters like time, field strength, solvent concentration, etc. Previously, our group focused on optimizing the EPD parameters of PtNP deposition on 2D flat targets. Varying diameters of these spherical NPs were coated on neural electrodes and their in vivo ...
Electrophoretic Deposition of Laser-generated Platinum- and Platinum-Alloy Nanoparticles onto Neural Electrode Surfaces
Platinum-based neural electrodes are used for implantation in the brain for recording neuronal activity and for acute or chronic neural stimulation, such as deep brain stimulation (DBS). For diseases like Parkinson’s, epilepsy, depression, deafness, spinal cord injuries, blindness, advanced tremors, etc., there is no complete cure. Therefore, to reduce the severity of the symptoms and to improve the patient’s quality of life, DBS is often performed. Although neural electrodes have been clinically used for a long time now, there are some drawbacks such as the increase in electrode impedance (Z) due to gliosis formation that reduces the efficacy of the electrodes to record or stimulate the neurons. Due to increasing Z, higher currents are required for better stimulation, which consequently reduces the battery life of the pulse generator. To eliminate these challenges faced by neurosurgeons, research has been carried out by modifying the surface topography using various methods to increase the electrochemical surface area (ECSA) and thereby reducing the Z. Various surface modification techniques have been employed for this purpose: chemical modifications, laser patterning, electrodeposition, vapor deposition, self-assembly, etc. One of the rising techniques is the electrophoretic deposition (EPD) of laser-generated ligand-free nanoparticles (NPs) onto platinum (Pt) electrode surfaces. It is one of the most versatile and simple methods without requiring complex equipment or processing tools. By the application of external electric fields, the colloidal NPs dispersed in water are subjected to a movement towards the oppositely charged electrode, on which the deposition takes place. The deposition output can be easily modified by simply adjusting the process parameters like time, field strength, solvent concentration, etc. Previously, our group focused on optimizing the EPD parameters of PtNP deposition on 2D flat targets. Varying diameters of these spherical NPs were coated on neural electrodes and their in vivo ...
Electrophoretic Deposition of Laser-generated Platinum- and Platinum-Alloy Nanoparticles onto Neural Electrode Surfaces
Ramesh, Vaijayanthi (author) / Barcikowski, Stephan
2023-12-01
Theses
Electronic Resource
English
| British Library Online Contents | 1997
First PEM fuel cell based on ligand-free, laser-generated platinum nanoparticles
| British Library Online Contents | 2019
Electrophoretic Deposition onto Ionic Liquid Layers
| British Library Online Contents | 2012
Effect of Flow Conditions on the Deposition of Platinum Nanoparticles on Stainless Steel Surfaces
| British Library Online Contents | 2015
Electrophoretic Deposition of Smectite Particles onto Cupper Plate
| British Library Online Contents | 2009