A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
In vivo degradation behavior of the magnesium alloy land442 in rabbit tibiae
In former studies the magnesium alloy LAE442 showed promising in vivo degradation behavior and biocompatibility. However, reproducibility might be enhanced by replacement of the rare earth composition metal "E" by only a single rare earth element. Therefore, it was the aim of this study to examine whether the substitution of "E" by neodymium ("Nd") had an influence on the in vivo degradation rate. LANd442 implants were inserted into rabbit tibiae and rabbits were euthanized after 4, 8, 13 and 26 weeks postoperatively. In vivo μCT was performed to evaluate the in vivo implant degradation behaviour by calculation of implant volume, density true 3-D thickness and corrosion rates. Additionally, weight loss, type of corrosion and mechanical stability were appraised by SEM/EDS-analysis and three-point bending tests. Implant volume, density and true 3-D thickness decreased over time, whereas the variance of the maximum diameters within an implant as well as the corrosion rate and weight loss increased. SEM examination revealed mainly pitting corrosion after 26 weeks. The maximum bending forces decreased over time. ; DFG/CRC/599
In vivo degradation behavior of the magnesium alloy land442 in rabbit tibiae
In former studies the magnesium alloy LAE442 showed promising in vivo degradation behavior and biocompatibility. However, reproducibility might be enhanced by replacement of the rare earth composition metal "E" by only a single rare earth element. Therefore, it was the aim of this study to examine whether the substitution of "E" by neodymium ("Nd") had an influence on the in vivo degradation rate. LANd442 implants were inserted into rabbit tibiae and rabbits were euthanized after 4, 8, 13 and 26 weeks postoperatively. In vivo μCT was performed to evaluate the in vivo implant degradation behaviour by calculation of implant volume, density true 3-D thickness and corrosion rates. Additionally, weight loss, type of corrosion and mechanical stability were appraised by SEM/EDS-analysis and three-point bending tests. Implant volume, density and true 3-D thickness decreased over time, whereas the variance of the maximum diameters within an implant as well as the corrosion rate and weight loss increased. SEM examination revealed mainly pitting corrosion after 26 weeks. The maximum bending forces decreased over time. ; DFG/CRC/599
In vivo degradation behavior of the magnesium alloy land442 in rabbit tibiae
Ullmann, Berit (author) / Reifenrath, Janin (author) / Dziuba, Dina (author) / Seitz, Jan-Marten (author) / Bormann, Dirk (author) / Meyer-Lindenberg, Andrea (author)
2011-01-01
Materials 4 (2011), Nr. 12
Article (Journal)
Electronic Resource
English
Bending force , Three-point bending test , Reproducibilities , μ-Computed tomography , Computerized tomography , Animal model , Pitting , Mechanical stability , Degradation behaviours , Rare earth compositions , Biocompatibility , Magnesium alloys , Magnesium alloy , Weight loss , Degradation , ddc:600 , ddc:624 , Sem examinations , Corrosion rate , Biodegradation
Degradation behaviour and mechanical properties of magnesium implants in rabbit tibiae
| British Library Online Contents | 2010
| British Library Online Contents | 2010
An Adjustable-Length Intramedullary Nail: Development and Mechanical Evaluation in Cervine Tibiae
| British Library Online Contents | 2015
| British Library Online Contents | 2019
Degradation Behavior of Magnesium Alloy AZ31 with Phosphate Conversion Film in Artificial Plasma
| British Library Online Contents | 2015