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Probabilistic mercury multimedia exposure assessment in small children and risk assessment
Objectives: Emissions of mercury in the environment have been decreasing for several years. However, mercury species are still found in different media (food, water, air and breast-milk). Due to mercury toxicity and typical behaviour in children, we have conducted a mercury exposure assessment in French babies, and small children aged 0 to 36 months. Method: Consumption and mercury concentration data were chosen for the exposure assessment. The Monte Carlo technique has been used to calculate the weekly exposure dose in order to integrate inter-individual variability and parameter uncertainty. Exposure values have been compared to toxicological reference values for health risk assessment. Results: Inorganic mercury median exposure levels ranged from 0.160 to 1.649 μg/kg of body weight per week (95th percentile (P95): 0.298–2.027 µg/kg bw/week); elemental mercury median exposure level in children was 0.11 ng/kg bw/week (P95: 28 ng/kg bw/week); and methylmercury median exposure level ranged from 0.247 to 0.273 µg/kg bw/week (P95: 0.425–0.463 µg/kg bw/week). Only elemental mercury by inhalation route (indoor air) and methylmercury by ingestion (fish and breast-milk) seem to lead to a health risk in small children. Conclusions: These results confirm the importance of assessing total mercury concentration in media like breast-milk, indoor air and dust and methylmercury level in food, other than fish and seafood. In this way, informed monitoring plan and risk assessment in an at-risk sub-population can be set. Keywords: Probabilistic exposure assessment, Multimedia, Mercury, Small children
Probabilistic mercury multimedia exposure assessment in small children and risk assessment
Objectives: Emissions of mercury in the environment have been decreasing for several years. However, mercury species are still found in different media (food, water, air and breast-milk). Due to mercury toxicity and typical behaviour in children, we have conducted a mercury exposure assessment in French babies, and small children aged 0 to 36 months. Method: Consumption and mercury concentration data were chosen for the exposure assessment. The Monte Carlo technique has been used to calculate the weekly exposure dose in order to integrate inter-individual variability and parameter uncertainty. Exposure values have been compared to toxicological reference values for health risk assessment. Results: Inorganic mercury median exposure levels ranged from 0.160 to 1.649 μg/kg of body weight per week (95th percentile (P95): 0.298–2.027 µg/kg bw/week); elemental mercury median exposure level in children was 0.11 ng/kg bw/week (P95: 28 ng/kg bw/week); and methylmercury median exposure level ranged from 0.247 to 0.273 µg/kg bw/week (P95: 0.425–0.463 µg/kg bw/week). Only elemental mercury by inhalation route (indoor air) and methylmercury by ingestion (fish and breast-milk) seem to lead to a health risk in small children. Conclusions: These results confirm the importance of assessing total mercury concentration in media like breast-milk, indoor air and dust and methylmercury level in food, other than fish and seafood. In this way, informed monitoring plan and risk assessment in an at-risk sub-population can be set. Keywords: Probabilistic exposure assessment, Multimedia, Mercury, Small children
Probabilistic mercury multimedia exposure assessment in small children and risk assessment
Typhaine Morisset (author) / Alejandra Ramirez-Martinez (author) / Nathalie Wesolek (author) / Alain-Claude Roudot (author)
2013
Article (Journal)
Electronic Resource
Unknown
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