A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
Abstract Polycyclic aromatic hydrocarbons (PAHs) are among the most toxic air pollutants in China. Efforts in assessing population inhalation exposure to PAHs, and its contribution to lung cancer risk for Chinese residents, have been limited due to insufficient data on measured indoor concentrations. A mass-balance model to predict indoor PAH concentrations was developed, along with estimated exposures and attributable lung cancer risks for residents in the Beijing region in 2006, with a 2-stage Monte Carlo simulation framework. The exposures and risks were split into three parts, based on the sources and places of exposure, to estimate the contributions of indoor and outdoor PAH sources and exposures, in order to better understand the source and place pattern of PAH exposure. PAHs bring considerable lung cancer risk to the population of Beijing region. The population attributable fraction (PAF) of lung cancer for Beijing's overall population is 2.99% [95% confidence interval (CI): 1.71%–4.26%]. Median contribution of indoor exposure to outdoor-originated PAHs (OUT–in) is 78% (CI: 73%–81%) in the overall population, for 97% (CI: 94%–99%) of whom OUT–in is the largest contributor. Rural residents are facing considerable exposure to indoor-originated PAHs (IN–in), which dominates the total exposure in 12% (CI: 2%–24%) of the rural population. This model framework could be used in quantitative comparison of different interventions on exposure to PAHs as well as other airborne pollutants.
Highlights ► We use Monte Carlo method to estimate PAH exposure with modeled indoor concentration. ► Uncertainty of the model is investigated with a 2-stage Monte Carlo technique. ► Key data pertinent to Beijing population is collected and presented in detail. ► Contributions of in/outdoor sources/exposures for urban/rural residents are analyzed. ► Population attributable fraction of lung cancer is calculated from exposure estimate.
Abstract Polycyclic aromatic hydrocarbons (PAHs) are among the most toxic air pollutants in China. Efforts in assessing population inhalation exposure to PAHs, and its contribution to lung cancer risk for Chinese residents, have been limited due to insufficient data on measured indoor concentrations. A mass-balance model to predict indoor PAH concentrations was developed, along with estimated exposures and attributable lung cancer risks for residents in the Beijing region in 2006, with a 2-stage Monte Carlo simulation framework. The exposures and risks were split into three parts, based on the sources and places of exposure, to estimate the contributions of indoor and outdoor PAH sources and exposures, in order to better understand the source and place pattern of PAH exposure. PAHs bring considerable lung cancer risk to the population of Beijing region. The population attributable fraction (PAF) of lung cancer for Beijing's overall population is 2.99% [95% confidence interval (CI): 1.71%–4.26%]. Median contribution of indoor exposure to outdoor-originated PAHs (OUT–in) is 78% (CI: 73%–81%) in the overall population, for 97% (CI: 94%–99%) of whom OUT–in is the largest contributor. Rural residents are facing considerable exposure to indoor-originated PAHs (IN–in), which dominates the total exposure in 12% (CI: 2%–24%) of the rural population. This model framework could be used in quantitative comparison of different interventions on exposure to PAHs as well as other airborne pollutants.
Highlights ► We use Monte Carlo method to estimate PAH exposure with modeled indoor concentration. ► Uncertainty of the model is investigated with a 2-stage Monte Carlo technique. ► Key data pertinent to Beijing population is collected and presented in detail. ► Contributions of in/outdoor sources/exposures for urban/rural residents are analyzed. ► Population attributable fraction of lung cancer is calculated from exposure estimate.
Population inhalation exposure to polycyclic aromatic hydrocarbons and associated lung cancer risk in Beijing region: Contributions of indoor and outdoor sources and exposures
Atmospheric Environment ; 62 ; 472-480
2012-08-28
9 pages
Article (Journal)
Electronic Resource
English
Contributions of indoor and outdoor sources to airborne polycyclic aromatic hydrocarbons indoors
| British Library Online Contents | 2018
Contributions of indoor and outdoor sources to airborne polycyclic aromatic hydrocarbons indoors
| British Library Online Contents | 2018
Contributions of indoor and outdoor sources to airborne polycyclic aromatic hydrocarbons indoors
| British Library Online Contents | 2018