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Are morphology and composition of gallstones related? An x-ray diffraction study
Abstract An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.
Are morphology and composition of gallstones related? An x-ray diffraction study
Abstract An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.
Are morphology and composition of gallstones related? An x-ray diffraction study
Bassi, N. (author) / Del Favero, G. (author) / Meggiato, T. (author) / Scalon, P. (author) / Ghiro, S. (author) / Molin, M. (author) / Pilotto, A. (author) / Vigneri, S. (author) / Savarino, V. (author) / Mela, G.S. (author)
Current Therapeutic Research - Clinical and Experimental ; 55 ; 1169-1175
1994-01-24
7 pages
Article (Journal)
Electronic Resource
English
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