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Halloysite-based hybrid bionanocomposite hydrogels as potential drug delivery systems
AbstractIn this investigation, the preparation of novel Halloysite-based chitosan/oxidized starch (Hal/CTS/OSR) Hybrid bionanocomposite hydrogels is described. The obtained hybrid hydrogels were characterized by using FT-IR, SEM, XRD, TGA and DTG techniques. In addition, the efficiency of hydrogels as drug delivery systems was studied. The results demonstrated that depending on experimental parameters, such as the ratio of CTS/OSR, and the type of Hal nanotubes (modified or unmodified), the hydrogel properties can be affected and modulated significantly. 74.3%, 71.2% and 69.45% MTZ release were observed for CTS/OSR/mHal 10, CTS/OSR and CTS/OSR/Hal 10 respectively.
Graphical abstract
HighlightsWe developed novel Halloysite-based bionanocomposite hydrogel beads.Incorporation of unmodified and modified Hal nanotubes effected significantly the hydrogel properties.MTZ release profile was studied.
Halloysite-based hybrid bionanocomposite hydrogels as potential drug delivery systems
AbstractIn this investigation, the preparation of novel Halloysite-based chitosan/oxidized starch (Hal/CTS/OSR) Hybrid bionanocomposite hydrogels is described. The obtained hybrid hydrogels were characterized by using FT-IR, SEM, XRD, TGA and DTG techniques. In addition, the efficiency of hydrogels as drug delivery systems was studied. The results demonstrated that depending on experimental parameters, such as the ratio of CTS/OSR, and the type of Hal nanotubes (modified or unmodified), the hydrogel properties can be affected and modulated significantly. 74.3%, 71.2% and 69.45% MTZ release were observed for CTS/OSR/mHal 10, CTS/OSR and CTS/OSR/Hal 10 respectively.
Graphical abstract
HighlightsWe developed novel Halloysite-based bionanocomposite hydrogel beads.Incorporation of unmodified and modified Hal nanotubes effected significantly the hydrogel properties.MTZ release profile was studied.
Halloysite-based hybrid bionanocomposite hydrogels as potential drug delivery systems
Sabbagh, Nooshin (author) / Akbari, Ali (author) / Arsalani, Nasser (author) / Eftekhari-Sis, Bagher (author) / Hamishekar, Hamed (author)
Applied Clay Science ; 148 ; 48-55
2017-08-06
8 pages
Article (Journal)
Electronic Resource
English
Halloysite-based hybrid bionanocomposite hydrogels as potential drug delivery systems
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