A platform for research: civil engineering, architecture and urbanism
Assessment of dietary exposure to organohalogen contaminants, legacy and emerging flame retardants in a Norwegian cohort
AbstractPolychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated diphenyl ethers (PBDEs), emerging halogenated flame retardants (EHFRs) and organophosphate flame retardants (PFRs) were detected in 24h duplicate diet samples from a Norwegian cohort (n=61), with concentrations ranging from <method limit of quantification (MLQ)-0.64ng/g ww, <MLQ-0.70ng/g ww, <MLQ-0.93ng/g ww, <MLQ-0.14ng/g ww, and <MLQ-150ng/g ww, respectively. All studied contaminants were detected in the duplicate diet samples with detection frequencies (DF) ranging from 1.6 to 98%. The major contaminants were CB153 (median 0.042ng/g ww), α-HCH (median 0.22ng/g ww), BDE209 (median 0.45ng/g ww), ethyl hexyl diphenyl phosphate (EHDPHP) (median 3.0ng/g ww) and bis(2-ethylhexyl)-3,4,5,6-tetrabromo-phthalate (BEH-TEBP) (<MLQ-0.14ng/g ww). Human dietary exposure assessment was conducted for each participant based on individual body weight and contaminant concentrations in their collected duplicate diet samples. The estimated median (95th percentile) dietary exposures for ΣPFR, ΣPCB, ΣOCP, ΣPBDE, and ΣEHFR were 87 (340), 5.8 (27), 11 (31), 1.3 (14), and <0.01 (3.4) ng/kgbw/day, respectively. The median and 95th percentile dietary exposures of most of the target analytes did not exceed the reference dose (RfD), except for PCBs where 16% of the participants exceeded the RfD. However, a relatively short period of such high intake is not expected to result in any adverse health effects. Participants of this cohort were exposed to higher levels of EHDPHP than any other FRs. Fish was the major dietary route for PCB, OCP and PBDE exposure, while meat was the main dietary exposure route for PFRs.
HighlightsFirst survey of EHFRs and PFRs in duplicate diet samplesEHDPHP was frequently detected in food samples at relatively high levels.Food might be the major pathway for human exposure to EHDPHP.PCBs and OCPs in the diet were linked to fish, while PFRs were linked to meat.
Assessment of dietary exposure to organohalogen contaminants, legacy and emerging flame retardants in a Norwegian cohort
AbstractPolychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated diphenyl ethers (PBDEs), emerging halogenated flame retardants (EHFRs) and organophosphate flame retardants (PFRs) were detected in 24h duplicate diet samples from a Norwegian cohort (n=61), with concentrations ranging from <method limit of quantification (MLQ)-0.64ng/g ww, <MLQ-0.70ng/g ww, <MLQ-0.93ng/g ww, <MLQ-0.14ng/g ww, and <MLQ-150ng/g ww, respectively. All studied contaminants were detected in the duplicate diet samples with detection frequencies (DF) ranging from 1.6 to 98%. The major contaminants were CB153 (median 0.042ng/g ww), α-HCH (median 0.22ng/g ww), BDE209 (median 0.45ng/g ww), ethyl hexyl diphenyl phosphate (EHDPHP) (median 3.0ng/g ww) and bis(2-ethylhexyl)-3,4,5,6-tetrabromo-phthalate (BEH-TEBP) (<MLQ-0.14ng/g ww). Human dietary exposure assessment was conducted for each participant based on individual body weight and contaminant concentrations in their collected duplicate diet samples. The estimated median (95th percentile) dietary exposures for ΣPFR, ΣPCB, ΣOCP, ΣPBDE, and ΣEHFR were 87 (340), 5.8 (27), 11 (31), 1.3 (14), and <0.01 (3.4) ng/kgbw/day, respectively. The median and 95th percentile dietary exposures of most of the target analytes did not exceed the reference dose (RfD), except for PCBs where 16% of the participants exceeded the RfD. However, a relatively short period of such high intake is not expected to result in any adverse health effects. Participants of this cohort were exposed to higher levels of EHDPHP than any other FRs. Fish was the major dietary route for PCB, OCP and PBDE exposure, while meat was the main dietary exposure route for PFRs.
HighlightsFirst survey of EHFRs and PFRs in duplicate diet samplesEHDPHP was frequently detected in food samples at relatively high levels.Food might be the major pathway for human exposure to EHDPHP.PCBs and OCPs in the diet were linked to fish, while PFRs were linked to meat.
Assessment of dietary exposure to organohalogen contaminants, legacy and emerging flame retardants in a Norwegian cohort
Xu, Fuchao (author) / Tay, Joo-Hui (author) / Covaci, Adrian (author) / Padilla-Sánchez, Juan Antonio (author) / Papadopoulou, Eleni (author) / Haug, Line Småstuen (author) / Neels, Hugo (author) / Sellström, Ulla (author) / de Wit, Cynthia A. (author)
Environmental International ; 102 ; 236-243
2017-03-14
8 pages
Article (Journal)
Electronic Resource
English
II-D Design of Solid Phase Active Organohalogen Flame Retardants
British Library Conference Proceedings | 2002
|