A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
Long-term exposure to mould/damp stains and mouldy odour increases low birth weight
https://orcid.org/0000-0002-0110-9492
https://orcid.org/0000-0002-5174-6668
https://orcid.org/0000-0001-8015-6299
https://orcid.org/0000-0003-4435-097X
Abstract Background Low birth weight (LBW), as a major concern in public health, is now increasing worldwide, but its main indoor environmental factors remain unclear. Objective We examined whether LBW including term-LBW (T-LBW) and preterm-LBW (P-LBW) was associated with maternal exposure to indoor environmental factors, with a purpose to identify the key indoor environmental factor(s) contributing to LBW. Methods A nationwide retrospective cohort study of 30,735 pre-schoolers in six Chinese cities was performed from 2010 to 2012. One questionnaire survey was conducted to collect information on the pre-schoolers’ birth outcomes and their maternal exposure of indoor environmental factors including new furniture, house redecoration, cooking fuels, mould/damp stains, and mouldy odour during pregnancy. Maternal exposure of traffic-related air pollutant (NO2), industrial pollutant (SO2), and inhalable particulate matter (PM10), as well as meteorological parameters, was estimated in pregnancy. Associations of LBW, T-LBW and P-LBW with indoor environmental factors were evaluated by two-level (city-child) logistic regression models with an odds ratio (OR) and 95% confidence interval (CI). Results We found that P-LBW (1.0%) and T-LBW (1.4%) prevalence were respectively associated with persistent mould/damp stains and mouldy odour exposure in utero, ORs = 1.81 (95% CI: 1.01–3.24) and 1.49 (95% CI: 1.01–2.21). Exposure to high temperature and PM2.5 in pregnancy significantly enhanced the effect of persistent mould/damp stains and/or mouldy odour on P-LBW and LBW, ORs (95% CI) = 2.92 (1.40–6.07) and 1.78 (1.00–3.15) with significant interaction p values of 0.067 and 0.094 respectively. Sensitivity analysis suggested that raising cats and dogs significantly increased LBW risk of persistent mould/damp stains and mouldy odour exposure. Conclusion Our findings indicate that long-term exposure to indoor mould/damp stains and mouldy odour in utero plays a key role in LBW, and this association can be significantly modified by some specific personal, indoor, and outdoor factors.
Graphical abstract Display Omitted
H I G H L I G H T S Mould/damp stains exposure was significantly associated with term-low birth weight (LBW). Maternal exposure to residential mouldy odour significantly increased the risk of preterm-LBW. High temperature and PM2.5 enhanced LBW risk of mould/damp stains and mouldy odour. Families with pets were more susceptible to LBW risk of mould/damp stains and mouldy odour. Our study has a new implication for the effective reduction and early prevention of LBW.
Long-term exposure to mould/damp stains and mouldy odour increases low birth weight
https://orcid.org/0000-0002-0110-9492
https://orcid.org/0000-0002-5174-6668
https://orcid.org/0000-0001-8015-6299
https://orcid.org/0000-0003-4435-097X
Abstract Background Low birth weight (LBW), as a major concern in public health, is now increasing worldwide, but its main indoor environmental factors remain unclear. Objective We examined whether LBW including term-LBW (T-LBW) and preterm-LBW (P-LBW) was associated with maternal exposure to indoor environmental factors, with a purpose to identify the key indoor environmental factor(s) contributing to LBW. Methods A nationwide retrospective cohort study of 30,735 pre-schoolers in six Chinese cities was performed from 2010 to 2012. One questionnaire survey was conducted to collect information on the pre-schoolers’ birth outcomes and their maternal exposure of indoor environmental factors including new furniture, house redecoration, cooking fuels, mould/damp stains, and mouldy odour during pregnancy. Maternal exposure of traffic-related air pollutant (NO2), industrial pollutant (SO2), and inhalable particulate matter (PM10), as well as meteorological parameters, was estimated in pregnancy. Associations of LBW, T-LBW and P-LBW with indoor environmental factors were evaluated by two-level (city-child) logistic regression models with an odds ratio (OR) and 95% confidence interval (CI). Results We found that P-LBW (1.0%) and T-LBW (1.4%) prevalence were respectively associated with persistent mould/damp stains and mouldy odour exposure in utero, ORs = 1.81 (95% CI: 1.01–3.24) and 1.49 (95% CI: 1.01–2.21). Exposure to high temperature and PM2.5 in pregnancy significantly enhanced the effect of persistent mould/damp stains and/or mouldy odour on P-LBW and LBW, ORs (95% CI) = 2.92 (1.40–6.07) and 1.78 (1.00–3.15) with significant interaction p values of 0.067 and 0.094 respectively. Sensitivity analysis suggested that raising cats and dogs significantly increased LBW risk of persistent mould/damp stains and mouldy odour exposure. Conclusion Our findings indicate that long-term exposure to indoor mould/damp stains and mouldy odour in utero plays a key role in LBW, and this association can be significantly modified by some specific personal, indoor, and outdoor factors.
Graphical abstract Display Omitted
H I G H L I G H T S Mould/damp stains exposure was significantly associated with term-low birth weight (LBW). Maternal exposure to residential mouldy odour significantly increased the risk of preterm-LBW. High temperature and PM2.5 enhanced LBW risk of mould/damp stains and mouldy odour. Families with pets were more susceptible to LBW risk of mould/damp stains and mouldy odour. Our study has a new implication for the effective reduction and early prevention of LBW.
Long-term exposure to mould/damp stains and mouldy odour increases low birth weight
https://orcid.org/0000-0002-0110-9492
https://orcid.org/0000-0002-5174-6668
https://orcid.org/0000-0001-8015-6299
https://orcid.org/0000-0003-4435-097X
Abstract Background Low birth weight (LBW), as a major concern in public health, is now increasing worldwide, but its main indoor environmental factors remain unclear. Objective We examined whether LBW including term-LBW (T-LBW) and preterm-LBW (P-LBW) was associated with maternal exposure to indoor environmental factors, with a purpose to identify the key indoor environmental factor(s) contributing to LBW. Methods A nationwide retrospective cohort study of 30,735 pre-schoolers in six Chinese cities was performed from 2010 to 2012. One questionnaire survey was conducted to collect information on the pre-schoolers’ birth outcomes and their maternal exposure of indoor environmental factors including new furniture, house redecoration, cooking fuels, mould/damp stains, and mouldy odour during pregnancy. Maternal exposure of traffic-related air pollutant (NO2), industrial pollutant (SO2), and inhalable particulate matter (PM10), as well as meteorological parameters, was estimated in pregnancy. Associations of LBW, T-LBW and P-LBW with indoor environmental factors were evaluated by two-level (city-child) logistic regression models with an odds ratio (OR) and 95% confidence interval (CI). Results We found that P-LBW (1.0%) and T-LBW (1.4%) prevalence were respectively associated with persistent mould/damp stains and mouldy odour exposure in utero, ORs = 1.81 (95% CI: 1.01–3.24) and 1.49 (95% CI: 1.01–2.21). Exposure to high temperature and PM2.5 in pregnancy significantly enhanced the effect of persistent mould/damp stains and/or mouldy odour on P-LBW and LBW, ORs (95% CI) = 2.92 (1.40–6.07) and 1.78 (1.00–3.15) with significant interaction p values of 0.067 and 0.094 respectively. Sensitivity analysis suggested that raising cats and dogs significantly increased LBW risk of persistent mould/damp stains and mouldy odour exposure. Conclusion Our findings indicate that long-term exposure to indoor mould/damp stains and mouldy odour in utero plays a key role in LBW, and this association can be significantly modified by some specific personal, indoor, and outdoor factors.
Graphical abstract Display Omitted
H I G H L I G H T S Mould/damp stains exposure was significantly associated with term-low birth weight (LBW). Maternal exposure to residential mouldy odour significantly increased the risk of preterm-LBW. High temperature and PM2.5 enhanced LBW risk of mould/damp stains and mouldy odour. Families with pets were more susceptible to LBW risk of mould/damp stains and mouldy odour. Our study has a new implication for the effective reduction and early prevention of LBW.
Long-term exposure to mould/damp stains and mouldy odour increases low birth weight
Lu, Chan (author) / Xiao, Fang (author) / Norbäck, Dan (author) / Yang, Xu (author) / Zhang, Yinping (author) / Li, Baizhan (author) / Zhao, Zhuohui (author) / Huang, Chen (author) / Zhang, Xin (author) / Qian, Hua (author)
Building and Environment ; 222
2022-07-13
Article (Journal)
Electronic Resource
English
Mouldy odour from soiled construction timber
| British Library Conference Proceedings | 1999
Mouldy odour and geosmin from soil-contaminated construction timber
| British Library Conference Proceedings | 2000
| British Library Conference Proceedings | 1996
| British Library Online Contents | 2017