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Exposure measurement error in air pollution studies: A framework for assessing shared, multiplicative measurement error in ensemble learning estimates of nitrogen oxides
Abstract Background Increasingly ensemble learning-based spatiotemporal models are being used to estimate residential air pollution exposures in epidemiological studies. While these machine learning models typically have improved performance, they suffer from exposure measurement error that is inherent in all models. Our objective is to develop a framework to formally assess shared, multiplicative measurement error (SMME) in our previously published three-stage, ensemble learning-based nitrogen oxides (NOx) model to identify its spatial and temporal patterns and predictors. Methods By treating the ensembles as an external dosimetry system, we quantified shared and unshared, multiplicative and additive (SUMA) measurement error components in our exposure model. We used generalized additive models (GAMs) with a smooth term for location to identify geographic locations with significantly elevated SMME and explain their spatial and temporal determinants. Results We found evidence of significant shared and unshared multiplicative error (p < 0.0001) in our ensemble-learning based spatiotemporal NOx model predictions. Unshared multiplicative error was 26 times larger than SMME. We observed significant geographic (p < 0.0001) and temporal variation in SMME with the majority (43%) of predictions with elevated SMME occurring in the earliest time-period (1992–2000). Densely populated urban prediction regions with complex air pollution sources generally exhibited highest odds of elevated SMME. Conclusions We developed a novel statistical framework to formally evaluate the magnitude and drivers of SMME in ensemble learning-based exposure models. Our framework can be used to inform building future improved exposure models.
Highlights Adapted a dosimetry statistical framework to quantify un/shared error in ensemble learning-based air pollution models. Identified locations of elevated shared multiplicative measurement error and explained their spatiotemporal determinants. Our framework informs building future improved spatiotemporal exposure models.
Exposure measurement error in air pollution studies: A framework for assessing shared, multiplicative measurement error in ensemble learning estimates of nitrogen oxides
Abstract Background Increasingly ensemble learning-based spatiotemporal models are being used to estimate residential air pollution exposures in epidemiological studies. While these machine learning models typically have improved performance, they suffer from exposure measurement error that is inherent in all models. Our objective is to develop a framework to formally assess shared, multiplicative measurement error (SMME) in our previously published three-stage, ensemble learning-based nitrogen oxides (NOx) model to identify its spatial and temporal patterns and predictors. Methods By treating the ensembles as an external dosimetry system, we quantified shared and unshared, multiplicative and additive (SUMA) measurement error components in our exposure model. We used generalized additive models (GAMs) with a smooth term for location to identify geographic locations with significantly elevated SMME and explain their spatial and temporal determinants. Results We found evidence of significant shared and unshared multiplicative error (p < 0.0001) in our ensemble-learning based spatiotemporal NOx model predictions. Unshared multiplicative error was 26 times larger than SMME. We observed significant geographic (p < 0.0001) and temporal variation in SMME with the majority (43%) of predictions with elevated SMME occurring in the earliest time-period (1992–2000). Densely populated urban prediction regions with complex air pollution sources generally exhibited highest odds of elevated SMME. Conclusions We developed a novel statistical framework to formally evaluate the magnitude and drivers of SMME in ensemble learning-based exposure models. Our framework can be used to inform building future improved exposure models.
Highlights Adapted a dosimetry statistical framework to quantify un/shared error in ensemble learning-based air pollution models. Identified locations of elevated shared multiplicative measurement error and explained their spatiotemporal determinants. Our framework informs building future improved spatiotemporal exposure models.
Exposure measurement error in air pollution studies: A framework for assessing shared, multiplicative measurement error in ensemble learning estimates of nitrogen oxides
Girguis, Mariam S. (author) / Li, Lianfa (author) / Lurmann, Fred (author) / Wu, Jun (author) / Urman, Robert (author) / Rappaport, Edward (author) / Breton, Carrie (author) / Gilliland, Frank (author) / Stram, Daniel (author) / Habre, Rima (author)
Environmental International ; 125 ; 97-106
2018-12-12
10 pages
Article (Journal)
Electronic Resource
English
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