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Biomonitoring Human Exposure to Household Air Pollution and Association with Self-reported Health Symptoms – A Stove Intervention Study in Peru
Abstract Background Household air pollution (HAP) from indoor biomass stoves contains harmful pollutants, such as polycyclic aromatic hydrocarbons (PAHs), and is a leading risk factor for global disease burden. We used biomonitoring to assess HAP exposure and association with self-reported symptoms in 334 non-smoking Peruvian women to evaluate the efficacy of a stove intervention program. Methods We conducted a cross-sectional study within the framework of a community randomized control trial. Using urinary PAH metabolites (OH-PAHs) as the exposure biomarkers, we investigated whether the intervention group (n =155, with new chimney-equipped stoves) were less exposed to HAP compared to the control group (n =179, with mostly open-fire stoves). We also estimated associations between the exposure biomarkers, risk factors, and self-reported health symptoms, such as recent eye conditions, respiratory conditions, and headache. Results We observed reduced headache and ocular symptoms in the intervention group than the control group. Urinary 2-naphthol, a suggested biomarker for inhalation PAH exposure, was significantly lower in the intervention group (GM with 95% CI: 13.4 [12.3, 14.6] μg/g creatinine) compared to control group (16.5 [15.0, 18.0] μg/g creatinine). Stove type and/or 2-naphthol was associated with a number of self-reported symptoms, such as red eye (adjusted OR with 95% CI: 3.80 [1.32, 10.9]) in the past 48h. Conclusions Even with the improved stoves, the biomarker concentrations in this study far exceeded those of the general populations and were higher than a no-observed-genotoxic-effect-level, indicating high exposure and a potential for increased cancer risk in the population.
Graphical abstract Prevalence of self-reported health symptoms in the control group (women using mostly traditional open-fire stoves) and intervention group (women using new chimney-equipped stoves). Display Omitted
Highlights New stove users had less headache and ocular symptoms than old stove users Household air pollution (HAP) was associated with headache and eye symptoms Even with the improved stoves, HAP exposure was high among the participants Exposure assessment is a useful tool for stove intervention studies Stove intervention programs should consider the durability of the new stove
Biomonitoring Human Exposure to Household Air Pollution and Association with Self-reported Health Symptoms – A Stove Intervention Study in Peru
Abstract Background Household air pollution (HAP) from indoor biomass stoves contains harmful pollutants, such as polycyclic aromatic hydrocarbons (PAHs), and is a leading risk factor for global disease burden. We used biomonitoring to assess HAP exposure and association with self-reported symptoms in 334 non-smoking Peruvian women to evaluate the efficacy of a stove intervention program. Methods We conducted a cross-sectional study within the framework of a community randomized control trial. Using urinary PAH metabolites (OH-PAHs) as the exposure biomarkers, we investigated whether the intervention group (n =155, with new chimney-equipped stoves) were less exposed to HAP compared to the control group (n =179, with mostly open-fire stoves). We also estimated associations between the exposure biomarkers, risk factors, and self-reported health symptoms, such as recent eye conditions, respiratory conditions, and headache. Results We observed reduced headache and ocular symptoms in the intervention group than the control group. Urinary 2-naphthol, a suggested biomarker for inhalation PAH exposure, was significantly lower in the intervention group (GM with 95% CI: 13.4 [12.3, 14.6] μg/g creatinine) compared to control group (16.5 [15.0, 18.0] μg/g creatinine). Stove type and/or 2-naphthol was associated with a number of self-reported symptoms, such as red eye (adjusted OR with 95% CI: 3.80 [1.32, 10.9]) in the past 48h. Conclusions Even with the improved stoves, the biomarker concentrations in this study far exceeded those of the general populations and were higher than a no-observed-genotoxic-effect-level, indicating high exposure and a potential for increased cancer risk in the population.
Graphical abstract Prevalence of self-reported health symptoms in the control group (women using mostly traditional open-fire stoves) and intervention group (women using new chimney-equipped stoves). Display Omitted
Highlights New stove users had less headache and ocular symptoms than old stove users Household air pollution (HAP) was associated with headache and eye symptoms Even with the improved stoves, HAP exposure was high among the participants Exposure assessment is a useful tool for stove intervention studies Stove intervention programs should consider the durability of the new stove
Biomonitoring Human Exposure to Household Air Pollution and Association with Self-reported Health Symptoms – A Stove Intervention Study in Peru
PhD, MPH, MS Li, Zheng (author) / Commodore, Adwoa (author) / Hartinger, Stella (author) / Lewin, Michael (author) / Sjödin, Andreas (author) / Pittman, Erin (author) / Trinidad, Debra (author) / Hubbard, Kendra (author) / Lanata, Claudio F. (author) / Gil, Ana I. (author)
Environmental International ; 97 ; 195-203
2016-09-13
9 pages
Article (Journal)
Electronic Resource
English
woodsmoke , household air pollution , stove intervention , polycyclic aromatic hydrocarbon , biomonitoring , 1-hydroxypyrene , PAH , OH-PAH , hydroxylated polycyclic aromatic hydrocarbon metabolite , CO , carbon monoxide , PM<inf>2.5</inf> , fine particulate matter with aerodynamic diameters <<hsp></hsp>2.5<hsp></hsp>μm , HAP , c-RCT , community randomized control trial
Human Biomonitoring in Occupational Health for Exposure Assessment
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