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Polybrominated diphenyl ethers and persistent organochlorines in Japanese human adipose tissues
AbstractThe present study determined concentrations of polybrominated diphenyl ethers (PBDEs) and persistent organochlorines (OCs) in Japanese human adipose tissues collected during 2003–2004. Concentrations of PBDEs in adipose tissues were 1–2 orders of magnitude lower than those of OCs. However, observed PBDE congener levels in this study were relatively higher than those in Japanese human adipose tissues collected during 2000 reported previously, while OC levels were comparable to those in specimens collected during 1999 reported by our group. In addition, no age-dependent accumulation of PBDEs was observed, while OC levels except chlordane compounds increased with age. These results indicate recent human exposure to PBDEs in Japan. Among PBDE congeners accumulated in Japanese adipose tissues, BDE-153 was dominant, but this trend was different from those in human milk (BDE-47) and blood (BDE-209) reported previously in Japan, implying the congener-specific kinetics in human bodies. The significant positive correlations between PBDEs and OCs were observed in Japanese adipose tissues, indicating the similar exposure route of these contaminants for Japanese citizens, probably via fish intake.
Polybrominated diphenyl ethers and persistent organochlorines in Japanese human adipose tissues
AbstractThe present study determined concentrations of polybrominated diphenyl ethers (PBDEs) and persistent organochlorines (OCs) in Japanese human adipose tissues collected during 2003–2004. Concentrations of PBDEs in adipose tissues were 1–2 orders of magnitude lower than those of OCs. However, observed PBDE congener levels in this study were relatively higher than those in Japanese human adipose tissues collected during 2000 reported previously, while OC levels were comparable to those in specimens collected during 1999 reported by our group. In addition, no age-dependent accumulation of PBDEs was observed, while OC levels except chlordane compounds increased with age. These results indicate recent human exposure to PBDEs in Japan. Among PBDE congeners accumulated in Japanese adipose tissues, BDE-153 was dominant, but this trend was different from those in human milk (BDE-47) and blood (BDE-209) reported previously in Japan, implying the congener-specific kinetics in human bodies. The significant positive correlations between PBDEs and OCs were observed in Japanese adipose tissues, indicating the similar exposure route of these contaminants for Japanese citizens, probably via fish intake.
Polybrominated diphenyl ethers and persistent organochlorines in Japanese human adipose tissues
Kunisue, Tatsuya (author) / Takayanagi, Nozomi (author) / Isobe, Tomohiko (author) / Takahashi, Shin (author) / Nose, Masato (author) / Yamada, Taketo (author) / Komori, Hiroaki (author) / Arita, Norimasa (author) / Ueda, Norifumi (author) / Tanabe, Shinsuke (author)
Environmental International ; 33 ; 1048-1056
2007-06-02
9 pages
Article (Journal)
Electronic Resource
English
PBDEs , OCs , Human adipose tissue , Japan
Polybrominated diphenyl ethers and persistent organochlorines in Japanese human adipose tissues
| Online Contents | 2007