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Transport pathways for arsenic and selenium: A minireview

Rosen, Barry P. / Liu, Zijuan

AbstractArsenic and selenium are metalloids found in the environment. Arsenic is considered to pose the most significant potential threat to human health based on frequency of occurrence, toxicity and human exposure. Selenium, on the other hand, ranks only 147th in toxicity but, in contrast to arsenic, is a required micronutrient. Whether a toxin or micronutrient, their metabolism requires that cells to accumulate these metalloids. In this review we discuss the membrane proteins that transport arsenic and selenium into cells, from bacteria to humans, as well as some of the efflux proteins involved in detoxification.

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Transport pathways for arsenic and selenium: A minireview

Rosen, Barry P. / Liu, Zijuan

AbstractArsenic and selenium are metalloids found in the environment. Arsenic is considered to pose the most significant potential threat to human health based on frequency of occurrence, toxicity and human exposure. Selenium, on the other hand, ranks only 147th in toxicity but, in contrast to arsenic, is a required micronutrient. Whether a toxin or micronutrient, their metabolism requires that cells to accumulate these metalloids. In this review we discuss the membrane proteins that transport arsenic and selenium into cells, from bacteria to humans, as well as some of the efflux proteins involved in detoxification.

Transport pathways for arsenic and selenium: A minireview

Rosen, Barry P. / Liu, Zijuan

AbstractArsenic and selenium are metalloids found in the environment. Arsenic is considered to pose the most significant potential threat to human health based on frequency of occurrence, toxicity and human exposure. Selenium, on the other hand, ranks only 147th in toxicity but, in contrast to arsenic, is a required micronutrient. Whether a toxin or micronutrient, their metabolism requires that cells to accumulate these metalloids. In this review we discuss the membrane proteins that transport arsenic and selenium into cells, from bacteria to humans, as well as some of the efflux proteins involved in detoxification.

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Title:

Transport pathways for arsenic and selenium: A minireview

Contributors:

Rosen, Barry P. (author) / Liu, Zijuan (author)

Published in:

Environmental International ; 35 ; 512-515

Publication date:

2008-01-01

Size:

4 pages

ISSN:

DOI:

https://doi.org/10.1016/j.envint.2008.07.023

Type of media:

Article (Journal)

Type of material:

Electronic Resource

Language:

English

Keywords:

Arsenic , Selenium , Toxin , Micronutrients

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