A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
Modified hydroxyapatite, composite bone cement as well as preparation method and application of modified hydroxyapatite and composite bone cement
The invention discloses modified hydroxyapatite, composite bone cement as well as a preparation method and application of the modified hydroxyapatite and the composite bone cement. The preparation method of the modified hydroxyapatite comprises the following steps: sintering hydroxyapatite and graphite to obtain the modified hydroxyapatite, the particle size D50 of the graphite is 10 nm to 48 [mu] m; the sintering temperature is 900 to 1700 DEG C; the sintering environment is vacuum or inert atmosphere. The prepared modified hydroxyapatite is compounded with magnesium phosphate bone cement, and the prepared composite bone cement has better photo-thermal conversion capability, photo-thermal anti-tumor performance and photo-thermal antibacterial performance, and is higher in cell adhesion rate, OD value and ALP activity.
本发明公开了一种改性羟基磷灰石、复合骨水泥及其制备方法和应用。该改性羟基磷灰石的制备方法包括以下步骤：羟基磷灰石与石墨进行烧结，得改性羟基磷灰石；所述石墨的粒径D50为10nm～48μm；所述烧结的温度为900～1700℃；所述烧结的环境为真空或惰性气氛。本发明制得的改性羟基磷灰石与磷酸镁骨水泥复配，制得的复合骨水泥具有较佳地光热转换能力、光热抗肿瘤和光热抗菌，且细胞粘附率、OD值和ALP活性均较高。
Modified hydroxyapatite, composite bone cement as well as preparation method and application of modified hydroxyapatite and composite bone cement
The invention discloses modified hydroxyapatite, composite bone cement as well as a preparation method and application of the modified hydroxyapatite and the composite bone cement. The preparation method of the modified hydroxyapatite comprises the following steps: sintering hydroxyapatite and graphite to obtain the modified hydroxyapatite, the particle size D50 of the graphite is 10 nm to 48 [mu] m; the sintering temperature is 900 to 1700 DEG C; the sintering environment is vacuum or inert atmosphere. The prepared modified hydroxyapatite is compounded with magnesium phosphate bone cement, and the prepared composite bone cement has better photo-thermal conversion capability, photo-thermal anti-tumor performance and photo-thermal antibacterial performance, and is higher in cell adhesion rate, OD value and ALP activity.
本发明公开了一种改性羟基磷灰石、复合骨水泥及其制备方法和应用。该改性羟基磷灰石的制备方法包括以下步骤：羟基磷灰石与石墨进行烧结，得改性羟基磷灰石；所述石墨的粒径D50为10nm～48μm；所述烧结的温度为900～1700℃；所述烧结的环境为真空或惰性气氛。本发明制得的改性羟基磷灰石与磷酸镁骨水泥复配，制得的复合骨水泥具有较佳地光热转换能力、光热抗肿瘤和光热抗菌，且细胞粘附率、OD值和ALP活性均较高。
Modified hydroxyapatite, composite bone cement as well as preparation method and application of modified hydroxyapatite and composite bone cement
一种改性羟基磷灰石、复合骨水泥及其制备方法和应用
SUN PING (author) / LI FENGQIAN (author) / ZHAN YANLEI (author) / HU HAI (author) / LAN SHENGHUI (author) / WEI JIE (author)
2022-06-14
Patent
Electronic Resource
Chinese
Modeling of the Curing Kinetics of an Acrylic Bone Cement Modified with Hydroxyapatite
| British Library Online Contents | 2003
| British Library Online Contents | 2018
| European Patent Office | 2022
Formation and Characterization of Bone-like Nanoscale Hydroxyapatite in Glass Bone Cement
| British Library Online Contents | 2004