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GALLIATED CALCIUM PHOSPHATE BIOMATERIALS
The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I): Ca (10.5-1.5x) Ga x (PO 4 ) 7 (I) wherein 0 < x < 1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca + Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5 % by weight. It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants. It further relates to a kit comprising a galliated calcium-phosphate biomaterial in combination with a fluid component. It finally relates to methods of use of the galliated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption.
GALLIATED CALCIUM PHOSPHATE BIOMATERIALS
The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I): Ca (10.5-1.5x) Ga x (PO 4 ) 7 (I) wherein 0 < x < 1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca + Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5 % by weight. It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants. It further relates to a kit comprising a galliated calcium-phosphate biomaterial in combination with a fluid component. It finally relates to methods of use of the galliated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption.
GALLIATED CALCIUM PHOSPHATE BIOMATERIALS
GALLIIERTE CALCIUMPHOSPHAT-BIOMATERIALIEN
BIOMATÉRIAUX DE PHOSPHATE DE CALCIUM AU GALLIUM
BUJOLI BRUNO (author) / BOULER JEAN-MICHEL (author) / JANVIER PASCAL (author) / KHAIROUN IBRAHIM (author) / SCHNITZLER VERENA (author) / MELLIER CHARLOTTE (author)
2018-11-14
Patent
Electronic Resource
English
IPC:
A61L
Verfahren oder Vorrichtungen zum Sterilisieren von Stoffen oder Gegenständen allgemein
,
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
/
A61K
Zubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke
,
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
/
C01B
NON-METALLIC ELEMENTS
,
Nichtmetallische Elemente
/
C04B
Kalk
,
LIME
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