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A platform for research: civil engineering, architecture and urbanism
SURFACE MODIFICATION METHOD FOR CERIA-STABLE ZIRCONIA-ALUMINA COMPOSITE CERAMIC MATERIAL
To provide a surface modification method for improving the biocompatibility of a ceria-stable zirconia-alumina composite ceramic material.SOLUTION: The present invention discloses a surface modification method for a ceria-stable zirconia-alumina composite ceramic material. In the surface modification method, the ceria-stable zirconia-alumina composite ceramic material is subjected to alkaline treatment and then plasma treatment, which can improve the differentiation of bone marrow mesenchymal cells into hard tissue, promote the angiogenesis of vascular endothelial cells, promote the formation of new bone when implanted in bone or reduce the occurrence of ROS upon contact with cells.SELECTED DRAWING: None
【課題】本発明は、セリア安定型ジルコニア－アルミナ複合セラミック材料の生体適合性を向上させるための表面改質方法を提供することを目的とする。【解決手段】セリア安定型ジルコニア－アルミナ複合セラミック材料の表面改質方法であって、セリア安定型ジルコニア－アルミナ複合セラミック材料をアルカリ処理した後、プラズマ処理を行うことにより、骨髄間葉細胞の硬組織への分化を向上させ、血管内皮細胞の血管新生を促進させ、骨埋入時の新生骨形成を促進させ、又は細胞接触時のＲＯＳ発生を低減させることができる、表面改質方法。【選択図】なし
SURFACE MODIFICATION METHOD FOR CERIA-STABLE ZIRCONIA-ALUMINA COMPOSITE CERAMIC MATERIAL
To provide a surface modification method for improving the biocompatibility of a ceria-stable zirconia-alumina composite ceramic material.SOLUTION: The present invention discloses a surface modification method for a ceria-stable zirconia-alumina composite ceramic material. In the surface modification method, the ceria-stable zirconia-alumina composite ceramic material is subjected to alkaline treatment and then plasma treatment, which can improve the differentiation of bone marrow mesenchymal cells into hard tissue, promote the angiogenesis of vascular endothelial cells, promote the formation of new bone when implanted in bone or reduce the occurrence of ROS upon contact with cells.SELECTED DRAWING: None
【課題】本発明は、セリア安定型ジルコニア－アルミナ複合セラミック材料の生体適合性を向上させるための表面改質方法を提供することを目的とする。【解決手段】セリア安定型ジルコニア－アルミナ複合セラミック材料の表面改質方法であって、セリア安定型ジルコニア－アルミナ複合セラミック材料をアルカリ処理した後、プラズマ処理を行うことにより、骨髄間葉細胞の硬組織への分化を向上させ、血管内皮細胞の血管新生を促進させ、骨埋入時の新生骨形成を促進させ、又は細胞接触時のＲＯＳ発生を低減させることができる、表面改質方法。【選択図】なし
SURFACE MODIFICATION METHOD FOR CERIA-STABLE ZIRCONIA-ALUMINA COMPOSITE CERAMIC MATERIAL
セリア安定型ジルコニア－アルミナ複合セラミック材料の表面改質方法
KOMASA SATOSHI (author) / TAKAO SEIJI (author) / OKAZAKI TEIJI (author) / YAMAZOE MASATOSHI (author) / MATSUURA RITARO (author) / KATO TAKAHIRO (author)
2022-02-25
Patent
Electronic Resource
Japanese
IPC:
A61K
Zubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke
,
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
/
A61L
Verfahren oder Vorrichtungen zum Sterilisieren von Stoffen oder Gegenständen allgemein
,
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
/
A61P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
,
Spezifische therapeutische Aktivität von chemischen Verbindungen oder medizinischen Zubereitungen
/
C04B
Kalk
,
LIME
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