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Monoclonal Antibody Detection of Chlorinated Benzenes on Contaminated Sediments
The modified soil ELISA, which eliminates the need for contaminant extraction prior to analysis, was demonstrated using crushed brick as a model soil matrix. Preliminary data were collected which tested for 1,2 -dichlorobenzene and 4-chloroaniline. Monoclonal antibodies were produced to three chlorobenzenes (chlorobenzene, 1,2-dichlorobenzene, 1,3-dichlorobenzene). Cross-reactivity experiments conducted with the antibodies to 4-chloroaniline showed strong differentiation between the target analyte and closely related chlorinated benzyl compounds. The antibodies to the chlorobenzenes continue to be used in developing a nonextractive soil immunoassay for chlorobenzenes. Immunoassay, Sediment testing, ELISA.
Monoclonal Antibody Detection of Chlorinated Benzenes on Contaminated Sediments
The modified soil ELISA, which eliminates the need for contaminant extraction prior to analysis, was demonstrated using crushed brick as a model soil matrix. Preliminary data were collected which tested for 1,2 -dichlorobenzene and 4-chloroaniline. Monoclonal antibodies were produced to three chlorobenzenes (chlorobenzene, 1,2-dichlorobenzene, 1,3-dichlorobenzene). Cross-reactivity experiments conducted with the antibodies to 4-chloroaniline showed strong differentiation between the target analyte and closely related chlorinated benzyl compounds. The antibodies to the chlorobenzenes continue to be used in developing a nonextractive soil immunoassay for chlorobenzenes. Immunoassay, Sediment testing, ELISA.
Monoclonal Antibody Detection of Chlorinated Benzenes on Contaminated Sediments
D. J. Mossman (author) / T. L. Feldbush (author)
1993
19 pages
Report
No indication
English
Solid Wastes Pollution & Control , Immunology , Chlorobenzene , Contaminants , Monoclonal antibodies , Sediments , Brick , Extraction , Immunoassay , Models , Soils , Targets , Detection , Anilines , Test and evaluation , Enzymes , 1 , 2-Dichlorobenzene , 4-Chloroaniline , Analytes , ELISA(Enzyme Linked Immuno Sorbent Assay)
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