A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
Mechanical ventilation has been used in critically ill patients for years to improve their ventilation and oxygenation. A new mode of mechanical ventilation called pressure regulated volume control (PRVC) has been developed which differs from the traditional modes of volume control (VC) and pressure control (PC) ventilation. The aim of this study was to investigate the differences in diaphragm shortening during PRVC versus VC and PC. Sprague Dawley rats were used and sequentially ventilated with PRVC, VC or PC. Within each mode, the tidal volume was increased from 3 ml to 12 ml in increments of 3 ml. Measurements of blood pressure, central venous pressure, diaphragm shortening, intrathoracic pressure, end-tidal CO2 and peak inspiratory pressure were taken throughout the experiment. There were no differences observed in the peak inspiratory pressure among the modes at all tidal volumes which suggests that compliances and airway resistances were the same for the three modes. In the PRVC mode, diaphragm shortening was significantly less than in the VC or PC mode. The difference in diaphragm shortening is believed to be associated to the changes in the resting length of the diaphragm. Consequently, PRVC affected the expansion of the chest differently than VC or PC. Further study of the movement of the diaphragm over long periods of ventilation is needed to understand the effect of this muscle when begin weaning from mechanical ventilation.
Mechanical ventilation has been used in critically ill patients for years to improve their ventilation and oxygenation. A new mode of mechanical ventilation called pressure regulated volume control (PRVC) has been developed which differs from the traditional modes of volume control (VC) and pressure control (PC) ventilation. The aim of this study was to investigate the differences in diaphragm shortening during PRVC versus VC and PC. Sprague Dawley rats were used and sequentially ventilated with PRVC, VC or PC. Within each mode, the tidal volume was increased from 3 ml to 12 ml in increments of 3 ml. Measurements of blood pressure, central venous pressure, diaphragm shortening, intrathoracic pressure, end-tidal CO2 and peak inspiratory pressure were taken throughout the experiment. There were no differences observed in the peak inspiratory pressure among the modes at all tidal volumes which suggests that compliances and airway resistances were the same for the three modes. In the PRVC mode, diaphragm shortening was significantly less than in the VC or PC mode. The difference in diaphragm shortening is believed to be associated to the changes in the resting length of the diaphragm. Consequently, PRVC affected the expansion of the chest differently than VC or PC. Further study of the movement of the diaphragm over long periods of ventilation is needed to understand the effect of this muscle when begin weaning from mechanical ventilation.
Effects of Three Modes of Mechanical Ventilation
J. Pierce (author)
1997
26 pages
Report
No indication
English
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