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Injectable Biodegradable Materials for Orthopaedic Tissue Engineering

Temenoff, J. S. / Mikos, A. G.

Abstract The large number of orthopaedic procedures performed each year, including many performed arthroscopically, has led to great interest in injectable biodegradable materials for regeneration of bone and cartilage. A variety of materials have been developed for these applications, including ceramics, naturally-derived substances and synthetic polymers. These materials demonstrate overall biocompatibility and appropriate mechanical properties, as well as promote tissue formation, thus providing an important step towards minimally invasive orthopaedic procedures. This review provides a comparison of these materials based on mechanical properties, biocompatibility and regeneration efficacy. Advantages and disadvantages of each material are explained and design criteria for injectable biodegradable systems are provided.

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Injectable Biodegradable Materials for Orthopaedic Tissue Engineering

Temenoff, J. S. / Mikos, A. G.

Abstract The large number of orthopaedic procedures performed each year, including many performed arthroscopically, has led to great interest in injectable biodegradable materials for regeneration of bone and cartilage. A variety of materials have been developed for these applications, including ceramics, naturally-derived substances and synthetic polymers. These materials demonstrate overall biocompatibility and appropriate mechanical properties, as well as promote tissue formation, thus providing an important step towards minimally invasive orthopaedic procedures. This review provides a comparison of these materials based on mechanical properties, biocompatibility and regeneration efficacy. Advantages and disadvantages of each material are explained and design criteria for injectable biodegradable systems are provided.

Injectable Biodegradable Materials for Orthopaedic Tissue Engineering

Temenoff, J. S. / Mikos, A. G.

Abstract The large number of orthopaedic procedures performed each year, including many performed arthroscopically, has led to great interest in injectable biodegradable materials for regeneration of bone and cartilage. A variety of materials have been developed for these applications, including ceramics, naturally-derived substances and synthetic polymers. These materials demonstrate overall biocompatibility and appropriate mechanical properties, as well as promote tissue formation, thus providing an important step towards minimally invasive orthopaedic procedures. This review provides a comparison of these materials based on mechanical properties, biocompatibility and regeneration efficacy. Advantages and disadvantages of each material are explained and design criteria for injectable biodegradable systems are provided.

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Title:

Injectable Biodegradable Materials for Orthopaedic Tissue Engineering

Contributors:

Temenoff, J. S. (author) / Mikos, A. G. (author)

Published in:

Polymer Based Systems on Tissue Engineering, Replacement and Regeneration ; 299-312

NATO Science Series ; 86

Publication date:

2002-01-01

Size:

14 pages

ISBN:

978-94-010-0305-6 , 978-1-4020-1001-9

ISSN:

DOI:

https://doi.org/10.1007/978-94-010-0305-6_16

Type of media:

Article/Chapter (Book)

Type of material:

Electronic Resource

Language:

English

Keywords:

Calcium Phosphate , Bone Cement , Calcium Phosphate Cement , Biphasic Calcium Phosphate , Sebacic Acid Chemistry , Biotechnology , Biomedicine general , Materials Science, general , Characterization and Evaluation of Materials , Biomedical Engineering , Orthopedics

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