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Porous Silicon Optical Label-Free Biosensors
Abstract Because of its large internal surface area, porous silicon (PSi) is an attractive material for chemical and biological sensing applications. This chapter describes label-free optical biosensors consisting of PSi photonic bandgap structures. After a brief review of the material science and key properties of PSi, the design, fabrication, and sensitivity of various PSi photonic bandgap structures is discussed. The properties of one type of these structures, namely PSi microcavities, are discussed in detail. The sensitivity of these structures is then verified experimentally via the detection of a single monolayer of silane and glutaraldehyde. Examples of biosensing are then discussed. They include the detection of DNA segments, Gram negative bacteria, IgG, and pathogenic E. coli.
Porous Silicon Optical Label-Free Biosensors
Abstract Because of its large internal surface area, porous silicon (PSi) is an attractive material for chemical and biological sensing applications. This chapter describes label-free optical biosensors consisting of PSi photonic bandgap structures. After a brief review of the material science and key properties of PSi, the design, fabrication, and sensitivity of various PSi photonic bandgap structures is discussed. The properties of one type of these structures, namely PSi microcavities, are discussed in detail. The sensitivity of these structures is then verified experimentally via the detection of a single monolayer of silane and glutaraldehyde. Examples of biosensing are then discussed. They include the detection of DNA segments, Gram negative bacteria, IgG, and pathogenic E. coli.
Porous Silicon Optical Label-Free Biosensors
Fauchet, Philippe M. (author)
2009-01-01
31 pages
Article/Chapter (Book)
Electronic Resource
English
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